Conopeptides from Cape Verde Conus crotchii [PDF]
Marine Cone snails of the genus Conus contain complex peptide toxins in their venom. Living in tropical habitats, they usually use the powerful venom for self-defense and prey capture.
Agostinho Antunes +14 more
core +1 more source
Novel conopeptides of the I-superfamily occur in several clades of cone snails [PDF]
The I-superfamily of conotoxins represents a new class of peptides in the venom of some Conus species. These toxins are characterized by four disulfide bridges and inhibit or modify ion channels of nerve cells.
Huys, I. +5 more
core +1 more source
Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails [PDF]
Venomous animals are thought to inject the same combination of toxins for both predation and defence, presumably exploiting conserved target pharmacology across prey and predators. Remarkably, cone snails can rapidly switch between distinct venoms in response to predatory or defensive stimuli.
Sébastien Dutertre +11 more
openalex +4 more sources
The emerging field of venom-microbiomics for exploring venom as a microenvironment, and the corresponding Initiative for Venom Associated Microbes and Parasites (iVAMP) [PDF]
Venom is a known source of novel antimicrobial natural products. The substantial, increasing number of these discoveries have unintentionally culminated in the misconception that venom and venom-producing glands are largely sterile environments.
Adams, Rachelle M.M. +13 more
core +1 more source
Friends or Foes? Emerging Impacts of Biological Toxins [PDF]
Toxins are substances produced from biological sources (e.g., animal, plants, microorganisms) that have deleterious effects on a living organism. Despite the obvious health concerns of being exposed to toxins, they are having substantial positive impacts
Casewell, N.R. +6 more
core +6 more sources
Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications
Background: Diverse and unique bioactive neurotoxins known as conopeptides or conotoxins are produced by venomous marine cone snails. Currently, these small and stable molecules are of great importance as research tools and platforms for discovering new ...
Maged M. A. Fouda +4 more
doaj +1 more source
Quo Vadis Venomics? A Roadmap to Neglected Venomous Invertebrates [PDF]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
Campbell, L, Jenner, R, von Reumont, B
core +2 more sources
Dietary breadth is positively correlated with venom complexity in cone snails [PDF]
AbstractAlthough diet is believed to be a major factor underlying the evolution of venom, few comparative studies examine both venom composition and diet across a radiation of venomous species. Cone snails within the family, Conidae, comprise more than 700 species of carnivorous marine snails that capture their prey by using a cocktail of venomous ...
Phuong, Mark A +2 more
openaire +4 more sources
Dramatic expansion of the black widow toxin arsenal uncovered by multi-tissue transcriptomics and venom proteomics. [PDF]
BackgroundAnimal venoms attract enormous interest given their potential for pharmacological discovery and understanding the evolution of natural chemistries.
Ayoub, Nadia A +4 more
core +2 more sources
The envenomation of general physiology throughout the last century. [PDF]
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
core +1 more source

