Results 51 to 60 of about 1,336 (154)

Organic Electrochemical Transistors for Neuromorphic Devices and Applications

Advanced Materials, Volume 38, Issue 9, 12 February 2026.
Organic electrochemical transistors are emerging as promising platforms for neuromorphic devices that emulate neuronal and synaptic activities and can seamlessly integrate with biological systems. This review focuses on resultant organic artificial neurons, synapses, and integrated devices, with an emphasis on their ability to perform neuromorphic ...
Kexin Xiang, Jiajun Song, Hong Liu, Junxin Chen, Feng Yan   +4 more
wiley   +1 more source

Hyperpolarization Modulation of the T‐Type hCav3.2 Channel by Human Synenkephalin [1–53], a Shrew Neurotoxin Analogue without Paralytic Effects

Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.
Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka, Yusuke Yano, Nozomi Hara, Chihiro Sadamoto, Andres D. Maturana, Masaki Kita   +5 more
wiley   +2 more sources

Conus vexillum venom induces oxidative stress in Ehrlich's ascites carcinoma cells: an insight into the mechanism of induction

Journal of Venomous Animals and Toxins including Tropical Diseases, 2013
Background It is estimated that venoms of marine cone snails (genus Conus) contain more than 100,000 different small peptides with a wide range of pharmacological and biological actions.
Mohamed A Abdel-Rahman, Ismail M Abdel-Nabi, Mohamed S El-Naggar, Osama A Abbas, Peter N Strong   +4 more
doaj   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Comparative Venomics of C. flavidus and C. frigidus and Closely Related Vermivorous Cone Snails

Marine Drugs, 2022
Cone snail venom biodiversity reflects dietary preference and predatory and defensive envenomation strategies across the ≈900 species of Conidae. To better understand the mechanisms of adaptive radiations in closely related species, we investigated the ...
S. W. A. Himaya, Alexander Arkhipov, Wai Ying Yum, Richard J. Lewis   +3 more
doaj   +1 more source

Advances in Bioinspired Interfacial Adhesion with Frictional Enhancement: From Fundamental Research to Biomimetic Applications

Small Structures, Volume 7, Issue 2, February 2026.
Biological models in nature reveal remarkable friction‐adhesion mechanisms, driven by intermolecular forces and suction. Researchers leverage these principles to design advanced materials with enhanced adhesion properties. By optimizing these materials under stimuli like light and electricity, new solutions emerge for regulating interface interactions ...
Yunfang Sun, Xuemin Yang, Guang Liu, Liwen Zhang, Yue Fu, Ping Li, Weiteng Li, Guang Yang, Huanyu Cheng, Huawei Chen   +9 more
wiley   +1 more source

Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails [PDF]

Nature Communications, 2014
Venomous animals are thought to inject the same combination of toxins for both predation and defence, presumably exploiting conserved target pharmacology across prey and predators. Remarkably, cone snails can rapidly switch between distinct venoms in response to predatory or defensive stimuli.
Dutertre, Sébastien, Jin, Ai-Hua, Vetter, Irina, Hamilton, Brett, Sunagar, Kartik, Lavergne, Vincent, Dutertre, Valentin, Fry, Bryan G., Antunes, Agostinho, Venter, Deon J., Alewood, Paul F., Lewis, Richard J.   +11 more
openaire   +5 more sources

A Transcriptomic Survey of Ion Channel-Based Conotoxins in the Chinese Tubular Cone Snail (Conus betulinus)

Marine Drugs, 2017
Conotoxins in the venom of cone snails (Conus spp.) are a mixture of active peptides that work as blockers, agonists, antagonists, or inactivators of various ion channels.
Yu Huang, Chao Peng, Yunhai Yi, Bingmiao Gao, Qiong Shi   +4 more
doaj   +1 more source

Coral Venom and Toxins as Protection Against Crown‐of‐Thorns Sea Star Attack

Molecular Ecology, Volume 35, Issue 1, January 2026.
ABSTRACT Crown‐of‐thorns sea star (CoTS) outbreaks are a main cause of hard coral cover decline across the Indo‐Pacific, posing a major threat to the resilience of coral reefs. However, the drivers underlying CoTS feeding on preferred (e.g., Acropora species) versus non‐preferred (e.g., Porites species) are poorly understood. We hypothesised that coral
Lucy M. Gorman, Ariana S. Huffmyer, Maria Byrne, Suzanne C. Mills, Hollie M. Putnam   +4 more
wiley   +1 more source

Protein engineering strategies to optimise recombinant product synthesis and accumulation in Nicotiana benthamiana

Plant Biotechnology Journal, Volume 24, Issue 1, Page 31-43, January 2026.
Summary In plant molecular farming, recombinant products include traditional protein targets, such as antibodies, antigens, and enzymes, but also increasingly refers to high‐value peptides, and small molecules produced by heterologous enzymatic pathways.
Maxim D. Harding, Frank Sainsbury
wiley   +1 more source