Results 31 to 40 of about 5,046 (227)

The Biological Role of Conoporins, Actinoporin-like Pore-Forming Toxins from Cone Snails [PDF]

Toxins
Cone snails are a large group of marine gastropods that produce a complex mixture of toxic compounds to hunt prey and defend against predators. The majority of the venom comprises small toxic peptides named conotoxins, which target membrane receptors. In
Matija Ruparčič, Gašper Šolinc, Simon Caserman, Juan Carlos Garcia Galindo, Manuel Jimenez Tenorio, Gregor Anderluh   +5 more
doaj   +2 more sources

Mass Spectrometry-based Sequencing of Venom Peptides (Conotoxins) from Vermivorous Cone Snail, Conus Loroisii: Toxicity of its Natural Venom

, 2021
Humaira Saleh Syed Rishimol R Arun Kumar J M Masilamani Selvam Rajesh R P 1.Molecular and nanomedicine Research Unit, Centre for nanoscience and nanotechnology, Sathyabama Institute of Science and Technology, Chennai, 600119, Tamil Nadu, India 2 ...
Humaira Saleh Syed, R Rishimol, Arun Kumar J, Masilamani Selvam, Rajaian Pushpabai Rajesh   +4 more
openalex   +2 more sources

Comparative analysis of venom genes in the chromosome-level genomes of two closely related cone snails

BMC Genomics
Background Venom cocktails of cone snails are characterized by their dynamic composition and the rapid evolution of toxin-encoding genes due to various selective pressures.
Ana Herráez-Pérez, Rafael Zardoya
doaj   +3 more sources

Cone snail milked venom dynamics – A quantitative study of Conus purpurascens [PDF]

Toxicon, 2012
Milked venom from cone snails represent a novel biological resource with a proven track record for drug discovery. To strengthen this correlation, we undertook a chromatographic and mass spectrometric study of individual milked venoms from Conus purpurascens.
Joycelyn B S, Chun, Margaret R, Baker, Do H, Kim, Majdouline, Leroy, Priamo, Toribo, Jon-Paul, Bingham   +5 more
openaire   +4 more sources

Predatory and Defensive Strategies in Cone Snails [PDF]

Toxins
Cone snails are carnivorous marine animals that prey on fish (piscivorous), worms (vermivorous), or other mollusks (molluscivorous). They produce a complex venom mostly made of disulfide-rich conotoxins and conopeptides in a compartmentalized venom gland.
Zahrmina Ratibou, Nicolas Inguimbert, Sébastien Dutertre   +2 more
doaj   +2 more sources

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

Marine Drugs, 2017
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world.
Samuel D. Robinson, Qing Li, Aiping Lu, Pradip K. Bandyopadhyay, Mark Yandell, Baldomero M. Olivera, Helena Safavi-Hemami   +6 more
doaj   +3 more sources

Author Correction: A structurally minimized yet fully active insulin based on cone-snail venom insulin principles [PDF]

Nature Structural & Molecular Biology, 2020
Xiaochun Xiong, John G. Menting, Maria M. Disotuar, Nicholas A. Smith, Carlie Delaine, Gabrielle Ghabash, Rahul Agrawal, Xiaomin Wang, Xiao He, Simon J. Fisher, Christopher A. MacRaild, Raymond S. Norton, Joanna Gajewiak, Briony E. Forbes, Brian J. Smith, Helena Safavi‐Hemami, Baldomero M. Olivera, Michael C. Lawrence, Danny Hung‐Chieh Chou   +18 more
semanticscholar   +3 more sources

Mass spectrometric identification and denovo sequencing of novel conotoxins from vermivorous cone snail (Conus inscriptus), and preliminary screening of its venom for biological activities in vitro and in vivo

Saudi Journal of Biological Sciences, 2020
Venom of Conus inscriptus, a vermivorous cone snail found abundantly in the southern coastal waters was studied to yield conotoxins through proteomic analysis.
Ruchi Jain, Benjamin Franklin Jayaseelan, Carlton Ranjith Wilson Alphonse, Ahmed Hossam Mahmoud, Osama B. Mohammed, Bandar M. AlMunqedhi, Rajesh Rajaian Pushpabai   +6 more
openalex   +2 more sources

HYBRID ECMO AND CONE SNAIL VENOM POISONING

Journal of the American College of Cardiology, 2022
Renato C. Ong, Marianne A. Florentino, R. Lapitan   +2 more
semanticscholar   +2 more sources

Fish-hunting cone snail disrupts prey's glucose homeostasis with weaponized mimetics of somatostatin and insulin. [PDF]

Nat Commun
Venomous animals have evolved diverse molecular mechanisms to incapacitate prey and defend against predators. Most venom components disrupt nervous, locomotor, and cardiovascular systems or cause tissue damage.
Yeung HY, Ramiro IBL, Andersen DB, Koch TL, Hamilton A, Bjørn-Yoshimoto WE, Espino S, Vakhrushev SY, Pedersen KB, de Haan N, Hipgrave Ederveen AL, Olivera BM, Knudsen JG, Bräuner-Osborne H, Schjoldager KT, Holst JJ, Safavi-Hemami H.   +16 more
europepmc   +2 more sources