Results 31 to 40 of about 1,336 (154)

Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications

Journal of Venomous Animals and Toxins including Tropical Diseases, 2021
Background: Diverse and unique bioactive neurotoxins known as conopeptides or conotoxins are produced by venomous marine cone snails. Currently, these small and stable molecules are of great importance as research tools and platforms for discovering new ...
Maged M. A. Fouda, Mohammed Abdel-Wahab, Amal Mohammadien, Mousa O. Germoush, Moustafa Sarhan   +4 more
doaj   +1 more source

The Mitochondrial Genome of the Venomous Cone Snail Conus consors

PLoS ONE, 2012
Cone snails are venomous predatory marine neogastropods that belong to the species-rich superfamily of the Conoidea. So far, the mitochondrial genomes of two cone snail species (Conus textile and Conus borgesi) have been described, and these feed on snails and worms, respectively.
Brauer, Age, Kurz, Alexander, Stockwell, Tim, Baden-Tillson, Holly, Heidler, Juliana, Wittig, Ilka, Kauferstein, Silke, Mebs, Dietrich, Stöcklin, Reto, Remm, Maido   +9 more
openaire   +5 more sources

Microhabitats within Venomous Cone Snails Contain Diverse Actinobacteria [PDF]

Applied and Environmental Microbiology, 2009
ABSTRACT Actinomycetes can be symbionts in diverse organisms, including both plants and animals. Some actinomycetes benefit their host by producing small molecule secondary metabolites; the resulting symbioses are often developmentally complex. Actinomycetes associated with three cone snails were studied.
Olivier, Peraud, Jason S, Biggs, Ronald W, Hughen, Alan R, Light, Gisela P, Concepcion, Baldomero M, Olivera, Eric W, Schmidt   +6 more
openaire   +2 more sources

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

Marine Drugs, 2017
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world.
Samuel D. Robinson, Qing Li, Aiping Lu, Pradip K. Bandyopadhyay, Mark Yandell, Baldomero M. Olivera, Helena Safavi-Hemami   +6 more
doaj   +1 more source

Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa [PDF]

Molecular Biology and Evolution, 2016
A specialized insulin was recently found in the venom of a fish-hunting cone snail, Conus geographus Here we show that many worm-hunting and snail-hunting cones also express venom insulins, and that this novel gene family has diversified explosively.
Safavi-Hemami, Helena, Lu, Aiping, Li, Qing, Fedosov, Alexander E., Biggs, Jason, Corneli, Patrice Showers, Seger, Jon, Yandell, Mark, Olivera, Baldomero M.   +8 more
openaire   +3 more sources

Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor

eLife, 2019
The fish-hunting marine cone snail Conus geographus uses a specialized venom insulin to induce hypoglycemic shock in its prey. We recently showed that this venom insulin, Con-Ins G1, has unique characteristics relevant to the design of new insulin ...
Peter Ahorukomeye, Maria M Disotuar, Joanna Gajewiak, Santhosh Karanth, Maren Watkins, Samuel D Robinson, Paula Flórez Salcedo, Nicholas A Smith, Brian J Smith, Amnon Schlegel, Briony E Forbes, Baldomero Olivera, Danny Hung-Chieh Chou, Helena Safavi-Hemami   +13 more
doaj   +1 more source

High-throughput prediction and characterization of antimicrobial peptides from multi-omics datasets of Chinese tubular cone snail (Conus betulinus)

Frontiers in Marine Science, 2022
Individual cone snail (Conus sp.) contains thousands of bioactive peptides, but there are limited studies on its antimicrobial peptides (AMPs). Here, we investigated AMPs along with AMP-derived genes in the representative Chinese tubular cone snail (C ...
Ruihan Li, Ruihan Li, Yu Huang, Chao Peng, Zijian Gao, Jie Liu, Xiaoting Yin, Xiaoting Yin, Xiaoting Yin, Bingmiao Gao, Tatiana V. Ovchinnikova, Limei Qiu, Limei Qiu, Chao Bian, Chao Bian, Qiong Shi, Qiong Shi   +16 more
doaj   +1 more source

Toxinology of Marine Venomous Snails

Iranian South Medical Journal, 2021
A surprisingly large number of sea snail species are venomous. Cone snail venoms are produced in a lengthy tubular duct from a complex venom gland and form a cocktail of many toxins, particularly conotoxins which have high potency and specificity for ...
Gholam Hossein Mohebbi, Iraj Nabipour
doaj  

In the picture: disulfide-poor conopeptides, a class of pharmacologically interesting compounds

Journal of Venomous Animals and Toxins including Tropical Diseases, 2016
During evolution, nature has embraced different strategies for species to survive. One strategy, applied by predators as diverse as snakes, scorpions, sea anemones and cone snails, is using venom to immobilize or kill a prey.
Eline K. M. Lebbe, Jan Tytgat
doaj   +1 more source

Elucidation of the molecular envenomation strategy of the cone snail Conus geographus through transcriptome sequencing of its venom duct

BMC Genomics, 2012
Background The fish-hunting cone snail, Conus geographus, is the deadliest snail on earth. In the absence of medical intervention, 70% of human stinging cases are fatal.
Hu Hao, Bandyopadhyay Pradip K, Olivera Baldomero M, Yandell Mark   +3 more
doaj   +1 more source