Results 11 to 20 of about 267,969 (148)
Venomics-Accelerated Cone Snail Venom Peptide Discovery [PDF]
International Journal of Molecular Sciences, 2018 Cone snail venoms are considered a treasure trove of bioactive peptides. Despite over 800 species of cone snails being known, each producing over 1000 venom peptides, only about 150 unique venom peptides are structurally and functionally characterized ...
Himaya Siddhihalu Wickrama Hewage +1 more
exaly +3 more sources
Stenotrophomonas-Like Bacteria Are Widespread Symbionts in Cone Snail Venom Ducts. [PDF]
Applied and Environmental Microbiology, 2017 Cone snails are biomedically important sources of peptide drugs, but it is not known whether snail-associated bacteria affect venom chemistry. To begin to answer this question, we performed 16S rRNA gene amplicon sequencing of eight cone snail species ...
Margo G. Haygood +2 more
exaly +3 more sources
Non-Peptidic Small Molecule Components from Cone Snail Venoms
Frontiers in Pharmacology, 2021 Venomous molluscs (Superfamily Conoidea) comprise a substantial fraction of tropical marine biodiversity (>15,000 species). Prior characterization of cone snail venoms established that bioactive venom components used to capture prey, defend against ...
Zhenjian Lin +14 more
doaj +4 more sources
Venom variation during prey capture by the cone snail, Conus textile. [PDF]
PLoS ONE, 2014 Observations of the mollusc-hunting cone snail Conus textile during feeding reveal that prey are often stung multiple times in succession. While studies on the venom peptides injected by fish-hunting cone snails have become common, these approaches have ...
Cecilia A Prator +2 more
doaj +2 more sources
Venom Diversity and Evolution in the Most Divergent Cone Snail Genus Profundiconus [PDF]
Toxins, 2019 Profundiconus is the most divergent cone snail genus and its unique phylogenetic position, sister to the rest of the family Conidae, makes it a key taxon for examining venom evolution and diversity. Venom gland and foot transcriptomes of Profundiconus cf.
Giulia Fassio +8 more
doaj +4 more sources
Venomics Reveals Venom Complexity of the Piscivorous Cone Snail, Conus tulipa [PDF]
Marine Drugs, 2019 The piscivorous cone snail Conus tulipa has evolved a net-hunting strategy, akin to the deadly Conus geographus, and is considered the second most dangerous cone snail to humans. Here, we present the first venomics study of C.
Mriga Dutt +5 more
doaj +2 more sources
Recruitment of Glycosyl Hydrolase Proteins in a Cone Snail Venomous Arsenal: Further Insights into Biomolecular Features of Conus Venoms [PDF]
Marine Drugs, 2012 Cone snail venoms are considered an untapped reservoir of extremely diverse peptides, named conopeptides, displaying a wide array of pharmacological activities.
Philippe Favreau +10 more
doaj +2 more sources
Diversity and Evolutionary Analysis of Venom Insulin Derived from Cone Snails
ToxinsCone snails possess a diverse array of novel peptide toxins, which selectively target ion channels and receptors in the nervous and cardiovascular systems. These numerous novel peptide toxins are a valuable resource for future marine drug development. In
Qiqi Guo +6 more
doaj +2 more sources
BMC Genomics, 2012 Background The fish-hunting cone snail, Conus geographus, is the deadliest snail on earth. In the absence of medical intervention, 70% of human stinging cases are fatal.
Hu Hao +3 more
doaj +2 more sources
Predatory and Defensive Strategies in Cone Snails
ToxinsCone snails are carnivorous marine animals that prey on fish (piscivorous), worms (vermivorous), or other mollusks (molluscivorous). They produce a complex venom mostly made of disulfide-rich conotoxins and conopeptides in a compartmentalized venom gland.
Zahrmina Ratibou +2 more
doaj +2 more sources