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Redistribution of Ancestral Functions Underlies the Evolution of Venom Production in Marine Predatory Snails. [PDF]
Zancolli G +6 more
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Cysteine pattern barcoding-based dataset filtration enhances the machine learning-assisted interpretation of Conus venom peptide therapeutics. [PDF]
Bibi R, Qasmi N, Rashid S.
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Profiling the Paralytic Effects and Lethality of Cone Snail Venom Toxins Using Nanofractionation Analytics with <i>In Vivo</i> Zebrafish Larvae Assays. [PDF]
Kool J +6 more
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Palaeo-oecological and palaeopathological observations on upper oligocene molluscs(Eger,Hungary) [PDF]
Dávid, Árpád
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Novel Pharmacological Targets From Indian Cone Snails
Mini-Reviews in Medicinal Chemistry, 2011The oceans are a source of combinatorial library of unique natural products, 'not found in the terrestrial environment'. Marine invertebrates such as sponges, molluscs, bryozoans, tunicates (Urochordata) and their associated microorganisms are the major representatives of promising bioactive compounds.
M Santhana, Ramasamy, S, Manikandan
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Peptide Neurotoxins from Fish-Hunting Cone Snails
Science, 1985To paralyze their more agile prey, the venomous fish-hunting cone snails ( Conus ) have developed a potent biochemical strategy. They produce several classes of toxic peptides (conotoxins) that attack a series of successive physiological targets in the neuromuscular system of the fish.
B M, Olivera +7 more
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Therapeutic Potential of Cone Snail Venom Peptides (Conopeptides)
Current Topics in Medicinal Chemistry, 2012Cone snails have evolved many 1000s of small, structurally stable venom peptides (conopeptides) for prey capture and defense. Whilst < 0.1% have been pharmacologically characterised, those with known function typically target membrane proteins of therapeutic importance, including ion channels, transporters and GPCRs. Several conopeptides reduce pain in
Vetter, Irina, Lewis, Richard J.
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