Results 91 to 100 of about 570,681 (325)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
mSystems, 2018 Mobile genetic elements such as conjugative plasmids are responsible for antibiotic resistance phenotypes in many bacterial pathogens. The ability to conjugate, the presence of antibiotics, and ecological interactions all have a notable role in the ...
Johannes Cairns +10 more
doaj +1 more source
Understanding Cross-Conjugation for Organic Electronics [PDF]
, 2019 Comunicación a congresopi-Conjugated organic molecules have been the focus of interest since they have been probed as potential semiconducting materials,[1] suitable for replacing the widely used silicon technologies.
Medina, Samara, Medina, Samara
core
Dark matter: A spin one half fermion field with mass dimension one?
, 2004 We report an unexpected theoretical discovery of a spin one half matter field with mass dimension one. It is based on a complete set of eigenspinors of the charge conjugation operator.
C. Rovelli +7 more
core +2 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Acetaminophen detoxification in cucumber plants via induction of glutathione S-transferases. [PDF]
, 2019 Many pharmaceutical and personal care products (PPCPs) enter agroecosystems during reuse of treated wastewater and biosolids, presenting potential impacts on plant development.
Dudley, Stacia +4 more
core
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Regular Objects, Multiplicative Unitaries and Conjugation
, 2002 The notion of left (resp. right) regular object of a tensor C*-category equipped with a faithful tensor functor into the category of Hilbert spaces is introduced. If such a category has a left (resp.
Pinzari, Claudia, Roberts, John E.
core +1 more source