Results 31 to 40 of about 75,295 (332)
Impact of genetic counseling and Connexin-26 and Connexin-30 testing on deaf identity and comprehension of genetic test results in a sample of deaf adults: a prospective, longitudinal study. [PDF]
PLoS ONE, 2014 Using a prospective, longitudinal study design, this paper addresses the impact of genetic counseling and testing for deafness on deaf adults and the Deaf community.
Christina G S Palmer +3 more
doaj +1 more source
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2013 Atherosclerosis, a chronic inflammatory disease of the vessel wall, involves multiple cell types of different origins, and complex interactions and signaling pathways between them. Autocrine and paracrine communication pathways provided by cytokines, chemokines, growth factors and lipid mediators are central to atherogenesis.
Pfenniger Anna +2 more
openaire +4 more sources
Cx43 channels and signaling via IP3/Ca2+, ATP, and ROS/NO propagate radiation-induced DNA damage to non-irradiated brain microvascular endothelial cells [PDF]
, 2020 Radiotherapeutic treatment consists of targeted application of radiation beams to a tumor but exposure of surrounding healthy tissue is inevitable.
Bultynck, Geert +10 more
core +1 more source
Diet-dependent immunohistochemical evaluation of connexin 43 in the sheep rumen [PDF]
, 2016 The objective of this study was to characterize the immunohistochemical localization of plasma membrane connexin 43 in the rumen of sheep after changing the diet from hay (ad libitum) to a mixed hay/concentrate diet.
Ahmed, Rasha S. +2 more
core +1 more source
Gap junction protein Connexin-43 is a direct transcriptional regulator of N-cadherin in vivo
Nature Communications, 2018 Connexins are the primary components of gap junctions, providing direct links between cells under many physiological processes. Here, we demonstrate that in addition to this canonical role, Connexins act as transcriptional regulators.
Maria P. Kotini +6 more
semanticscholar +1 more source
Connexin Hemichannels in Astrocytes: Role in CNS Disorders
Frontiers in Molecular Neuroscience, 2019 In the central nervous system (CNS), astrocytes form networks interconnected by gap junctions made from connexins of the subtypes Cx30 and Cx43. When unopposed by an adjoining hemichannel, astrocytic connexins can act as hemichannels to control the ...
Lingyan Xing +3 more
semanticscholar +1 more source
Cellular Physiology and Biochemistry, 2016 Aims: Connexin 43 is one of the most potent gap junction proteins related to osteoblast differentiation and bone formation. We hypothesized that Connexin 43 is a significant factor in osteogenic differentiation in the posterior longitudinal ligament ...
Haisong Yang +6 more
doaj +1 more source
BMC Medicine, 2008 Background The modulation of gap junctional communication between tumor cells and between tumor and vascular endothelial cells during tumorigenesis and metastasis is complex.
Gillespie Mark N +5 more
doaj +1 more source
Extracellular cysteine in connexins: Role as redox sensors [PDF]
, 2016 Indexación: Scopus.Connexin-based channels comprise hemichannels and gap junction channels. The opening of hemichannels allow for the flux of ions and molecules from the extracellular space into the cell and vice versa.
Báez, D. +7 more
core +2 more sources
Journal of Experimental & Clinical Cancer Research, 2010 Background bFGF is an important growth factor for glioma cell proliferation and invasion, while connexin 43 is implicated in the suppression of glioma growth.
Liu Hongsheng +5 more
doaj +1 more source