Results 61 to 70 of about 75,295 (332)
Expression of connexins in human preimplantation embryos in vitro [PDF]
, 2004 Intercellular communication via gap junctions is required to coordinate developmental processes in the mammalian embryo. We have investigated if the connexin (Cx) isoforms known to form gap junctions in rodent preimplantation embryos are also expressed ...
Bloor, D.J. +6 more
core +4 more sources
BMC Genomics, 2020 Background Based on an initial collecting of database sequences from the gap junction protein gene family (also called connexin genes) in a few teleosts, the naming of these sequences appeared variable. The reasons could be (i) that the structure in this
Svein-Ole Mikalsen +2 more
doaj +1 more source
Connexins and Integrins in Exosomes [PDF]
Cancers, 2019 Connexins and integrins, the two structurally and functionally distinct families of transmembrane proteins, have been shown to be inter-connected by various modes of cross-talk in cells, such as direct physical coupling via lateral contact, indirect physical coupling via actin and actin-binding proteins, and functional coupling via signaling cascades ...
Motomu Shimaoka +4 more
openaire +3 more sources
Effects of candesartan, an angiotensin II receptor type I blocker, on atrial remodeling in spontaneously hypertensive rats [PDF]
, 2015 Hypertension-induced structural remodeling of the left atrium (LA) has been suggested to involve the renin–angiotensin system. This study investigated whether treatment with an angiotensin receptor blocker, candesartan, regresses atrial remodeling in ...
Choisy, Stéphanie C. +5 more
core +1 more source
Connexin 43-Based Therapeutics for Dermal Wound Healing
International Journal of Molecular Sciences, 2018 The most ubiquitous gap junction protein within the body, connexin 43 (Cx43), is a target of interest for modulating the dermal wound healing response. Observational studies found associations between Cx43 at the wound edge and poor healing response, and
Jade Montgomery +4 more
semanticscholar +1 more source
Connexins in Astrocyte Migration [PDF]
Frontiers in Pharmacology, 2020 Astrocytes have long been considered the supportive cells of the central nervous system, but during the last decades, they have gained much more attention because of their active participation in the modulation of neuronal function. For example, after brain damage, astrocytes become reactive and undergo characteristic morphological and molecular ...
Raúl Lagos-Cabré +6 more
openaire +4 more sources
International Journal of Molecular Sciences, 2018 The heart is a complex organ composed of multiple cell types, including cardiomyocytes and different non-myocyte populations, all working closely together to determine the hearts properties and maintain normal cardiac function.
Robert D Johnson, P. Camelliti
semanticscholar +1 more source
Gap junction proteins and their role in spinal cord injury
Frontiers in Molecular Neuroscience, 2015 Gap junctions are specialized intercellular communication channels that are formed by two hexameric connexin hemichannels, one provided by each of the two adjacent cells.
Ryan S Tonkin +6 more
doaj +1 more source
Inner Ear Connexin Channels: Roles in Development and Maintenance of Cochlear Function.
Cold Spring Harbor Perspectives in Medicine, 2018 Connexin 26 and connexin 30 are the prevailing isoforms in the epithelial and connective tissue gap junction systems of the developing and mature cochlea.
F. Mammano
semanticscholar +1 more source
Frontiers in Cellular Neuroscience, 2019 A variety of glial cell functions are supported by connexin and pannexin proteins. These functions include the modulation of synaptic gain, the control of excitability through regulation of the ion and neurotransmitter composition of the extracellular ...
Lucila Brocardo +3 more
doaj +1 more source