Results 71 to 80 of about 27,985 (262)

Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies [PDF]

open access: yes, 1992
We examined the roles of the extracellular domains of a gap junction protein and a cell adhesion molecule in gap junction and adherens junction formation by altering cell interactions with antibody Fab fragments.
Johnson, Ross G.   +3 more
core   +2 more sources

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

open access: yesHepatology Research, EarlyView.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura   +11 more
wiley   +1 more source

What's the Function of Connexin 32 in the Peripheral Nervous System? [PDF]

open access: yes, 2018
Connexin 32 (Cx32) is a fundamental protein in the peripheral nervous system (PNS) as its mutations cause the X-linked form of Charcot-Marie-Tooth disease (CMT1X), the second most common form of hereditary motor and sensory neuropathy and a demyelinating
Bortolozzi, Mario
core   +1 more source

Connexin 46 and Connexin 50 in Selenite Cataract

open access: yesOphthalmic Research, 2005
The purpose of this work was to determine if the lens gap junction proteins connexin 46 (Cx46) and connexin 50 (Cx50) were altered with the development of selenite-induced cataract. Cataracts were induced in young Sprague-Dawley rats with a single subcutaneous injection of sodium selenite; age-matched uninjected rats served as controls.
openaire   +2 more sources

Understanding Atrial Fibrillation Complexity Through the Lens of Turbulence Dynamics: Implications for Treatment Strategies

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. Its incidence increases significantly with age and has become a major global public health issue. Although research into the mechanisms of AF has spanned over a century‐ranging from the reentry theory to the rotor hypothesis‐none of these
Xin Chu   +4 more
wiley   +1 more source

Trafficking pathways of Cx49-GFP in living mammalian cells [PDF]

open access: yes, 2005
In the present study we examined the trafficking pathways of connexin49 (Cx49) fused to green fluorescent protein (GFP) in polar and non-polar cell lines. The Cx49 gene was isolated from ovine lens by RT-PCR.
Breidert, Stephanie   +4 more
core   +2 more sources

Transcriptomic Remodeling of Pulmonary Vein Sleeves Suggests a Role in Atrial Arrhythmogenesis in Thoroughbred Horses

open access: yesAnnals of the New York Academy of Sciences, EarlyView.
Myocardial sleeves of the pulmonary veins in racehorses with paroxysmal atrial fibrillation exhibit upregulated pathways associated with tissue structure remodeling. Pathways related to the extracellular matrix and cellular components differ significantly from those in healthy horses.
Magdalena Arevalo‐Turrubiarte   +8 more
wiley   +1 more source

Connexin36 knockout mice display increased sensitivity to pentylenetetrazol-induced seizure-like behaviors [PDF]

open access: yes, 2010
Large-scale synchronous firing of neurons during seizures is modulated by electrotonic coupling between neurons via gap junctions. To explore roles for connexin36 (Cx36) gap junctions in seizures, we examined the seizure threshold of connexin36 knockout (
Cursons, Raymond T.   +7 more
core   +2 more sources

Functional analysis of connexin‐26 mutants associated with hereditary recessive deafness [PDF]

open access: bronze, 2003
Hung‐Li Wang   +6 more
openalex   +1 more source

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