Results 61 to 70 of about 1,008 (160)
[Retracted] A Showcase of Bench‐to‐Bedside Regenerative Medicine at the 2010 ASNTR
The Scientific World Journal, Volume 11, Issue 1, Page 1842-1864, 2011., 2011 Insight into the expanding themes of regenerative medicine is provided by the American Society for Neural Therapy and Repair′s annual meeting. The 17th meeting covered a wide range of neurodegenerative disorders, exploring methods to elucidate the currently unknown mechanisms behind the disorders, as well as possible treatments ranging from the use of ...
David J. Eve +3 more
wiley +1 more source
Prey specificity of predatory venoms
Biological Reviews, Volume 99, Issue 6, Page 2253-2273, December 2024.ABSTRACT Venom represents a key adaptation of many venomous predators, allowing them to immobilise prey quickly through chemical rather than physical warfare. Evolutionary arms races between prey and a predator are believed to be the main factor influencing the potency and composition of predatory venoms.
Ondřej Michálek +2 more
wiley +1 more source
Computational and Structural Biotechnology Journal, 2020 Chronic neuropathic pain is the most complex and challenging clinical problem of a population that sets a major physical and economic burden at the global level. Ca2+-permeable channels functionally orchestrate the processing of pain signals. Among them,
Sameera, Fawad Ali Shah, Sajid Rashid
doaj +1 more source
Journal of Peptide Science, Volume 30, Issue 11, November 2024.This review provides an overview of FDA‐approved peptides, particularly those targeting cardiovascular diseases, human immunodeficiency, and central nervous system diseases, and also addresses conditions such as osteoporosis, thrombocytopenia, Cushing's disease, and hypoglycemia.
Othman Al Musaimi
wiley +1 more source
ACADEMIA JOURNAL OF BIOLOGYMosquitoes are carriers of various diseases that result in millions of human deaths annually. However, the use of chemical mosquitocides has led to significant concerns, such as adverse effects on the environment, human health, and insecticide resistance.
B. Nguyen +3 more
semanticscholar +1 more source
Scientific Reports, 2018 We here describe a novel α-conopeptide, Eu1.6 from Conus eburneus, which exhibits strong anti-nociceptive activity by an unexpected mechanism of action.
Zhuguo Liu +14 more
semanticscholar +1 more source
α-Conopeptides specifically expressed in the salivary gland of Conus pulicarius [PDF]
Toxicon, 2008 To date, studies conducted on cone snail venoms have attributed the origins of this complex mixture of neuroactive peptides entirely to gene expression by the secretory cells lining the lumen of the venom duct. However, specialized tissues such as the salivary glands also secrete their contents into the anterior gut and could potentially contribute ...
Jason S, Biggs +2 more
openaire +2 more sources
New Conotoxin SO-3 Targeting N-type Voltage-Sensitive Calcium Channels
Marine Drugs, 2006 Selective blockers of the N-type voltage-sensitive calcium (CaV) channels are useful in the management of severe chronic pain. Here, the structure and function characteristics of a novel N-type CaV channel blocker, SO-3, are reviewed.
Lei Wen +4 more
doaj +1 more source
PLoS ONE, 2007 Little is known about the molecular basis of somatosensory mechanotransduction in mammals. We screened a library of peptide toxins for effects on mechanically activated currents in cultured dorsal root ganglion neurons.
Liam J Drew +11 more
doaj +1 more source
The FASEB Journal, Volume 38, Issue 1, 15 January 2024.Analogs of α‐conotoxin PnIC selectively inhibit α7β2‐ over α7‐only subtype nicotinic acetylcholine receptors via a novel allosteric mechanism.Andrew A. George, Sabin J. John, Linda M. Lucero, J. Brek Eaton, Ekta Jaiswal, Sean B. Christensen, Joanna Gajewiak, Maren Watkins, Yiwei Cao, Baldomero M. Olivera, Wonpil Im, J.
Andrew A. George +12 more
wiley +1 more source