Results 81 to 90 of about 1,537,452 (154)

Eukaryotic DNA Mismatch Repair In Vitro

, 2012
Mismatch repair corrects biosynthetic errors generated during DNA replication. Mismatch repair deficiency causes a mutator phenotype and directly underlies hereditary nonpolyposis colorectal cancer and some sporadic cancers.
Yuan, Fenghua, Liu, Fengsong, Gu, Liya, Song, Limin, Fengsong Liu, Liya Gu, Fenghua Yuan, Yanbin Zhang, Limin Song, Zhang, Yanbin   +9 more
core   +1 more source

Claiming the Isle? Islandness and Territorial Demands

Nations and Nationalism, EarlyView.
ABSTRACT This article explores the relationship between insularity and territorial demands, focusing on whether island territories are more likely to support regionalist and secessionist parties. To address this question, we compare electoral support for such parties across island and mainland territories using a large‐N dataset.
Pau Torres, Marc Sanjaume‐Calvet
wiley   +1 more source

Concomitant IDH-wildtype glioblastoma and IDH1-mutant anaplastic astrocytoma in a patient with constitutional mismatch repair deficiency syndrome

, 2017
Constitutional mismatch repair deficiency (CMMRD) is a rare and often under-recognized tumour predisposition syndrome, presenting with both extracranial and malignant brain tumours that occur in children and/or young adults [1].
Tabori, Uri, OPOCHER, ENRICO, Fassan, Matteo, Arcella, Antonella, Gardiman, Marina Paola, Quaia, Michele, Viel, Alessandra, D'Avella, Domenico, Kelly, Jacalyn, Rivieri, Francesca, Campbell, Britany, Edwards, Melissa, Galuppini, Francesca, Giangaspero, Felice, Mammi, Isabella   +14 more
core   +1 more source

Sovereignty Without Surveillance: Regulatory Voids and the Limits of Marine Governance in Bougainville

Pacific Focus, EarlyView.
ABSTRACT This article investigates the regulatory voids that undermine sovereign marine governance in the Autonomous Region of Bougainville, with a focus on the Pirung Wildlife Management Area (WMA). Based on fieldwork conducted in January 2025, including data collected from 50 community members and 25 government officials, the study reveals that ...
Kai Hang, Alessandro Rocco Prestia, Jeffery Noro   +2 more
wiley   +1 more source

Powers and Practices in Labor Standards Enforcement

Regulation &Governance, EarlyView.
ABSTRACT Wage theft remains a pervasive problem internationally and within the United States. In response, worker advocates have sought stronger laws to deter violations and promote compliance. Yet formal authority alone may be insufficient; labor departments often fail to use the full extent of their legal authority to conduct vigorous enforcement ...
Daniel J. Galvin, Hana Shepherd, Jenn Round, Jake Barnes, Janice Fine   +4 more
wiley   +1 more source

Three Configurations of In‐House Government Consulting: Public‐Value Purpose and Organizational Viability

Governance, Volume 39, Issue 4, December 2026.
ABSTRACT Governments have created in‐house consulting organizations to reduce dependence on external firms and retain public capability and control. Yet organizations grouped under this label pursue different forms of public value that require different designs.
Sean Safford
wiley   +1 more source

Environmental Justice in the Brazilian Coastal Food Systems: Policies, Institutions, and Knowledges on Small‐Scale Fishers and Energy Development

World Food Policy, Volume 12, Issue 2, November 2026.
ABSTRACT This study explores environmental justice issues in coastal food systems, focusing on conflicts between small‐scale fisheries and the energy sector due to differing goals in managing food and energy sources. It does so by examining the interdependence between institutions, policies, and different types of knowledge; key elements in building ...
Mateus Henrique Amaral, Lira Luz Benites Lazaro, Rosie Day, Lindsay C. Stringer, Leandra Regina Gonçalves, Aline Martins de Carvalho, Leandro Luiz Giatti   +6 more
wiley   +1 more source

Colorectal cancers associated with mismatch repair deficiency

Frontiers in Medicine
This review aims to summarize the latest updates in the prevention, diagnosis, treatment and management of colorectal cancers (CRCs) associated with mutation(s) or alteration(s) in the DNA mismatch repair (MMR) genes.
Mingzhu Sun, Kevin Monahan, Kevin Monahan, Jayne Moquet, Stephen Barnard   +4 more
doaj   +1 more source

Synergistic Effect of High Strength‐Grain Refinement and Suppression of Al6Fe Phase Coarsening in Additively Manufactured Al‐Fe‐Sc‐Zr Alloys via Mg Addition

Rare Metals, Volume 45, Issue 10, October 2026.
ABSTRACT To meet the demand for high‐performance lightweight heat‐resistant materials in aerospace and automotive applications, a novel Al‐Fe‐Sc‐Zr heat‐resistant aluminum alloy was fabricated by laser powder bed fusion (L‐PBF). The effects of Mg content (1 wt%, 3 wt%, 5 wt%, and 7 wt%) on formability, microstructure, mechanical properties, and thermal
Xinyu Du, Jibing Chen, Yanfeng Liu, Yueting Wang, Ruidi Li, Liang He, Hongze Wang   +6 more
wiley   +1 more source

Beyond the Border Wars: Representation, Scale, and Multi‐Member Districts

Geographical Analysis, Volume 58, Issue 4, October 2026.
ABSTRACT Proposed redistricting reforms often focus on fixing gerrymandered maps or restructuring elections to boost proportionality. Recent work shows that, averaged across all 50 states, multi‐member districts paired with proportional ranked‐choice voting can deliver near‐proportional outcomes while curbing the gains available to a partisan map ...
Christopher S. Fowler, Linda L. Fowler
wiley   +1 more source