Results 131 to 140 of about 5,156 (193)

Direct activation of Constitutive Androstane Receptor by Phthalates [PDF]

Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016), 2017
Huiming CHEN, Hui HAN, Wenping XIE, Wenchao AI, Guolin SHEN, Haishan LI   +5 more
openaire   +1 more source

Methadone induces the expression of hepatic drug-metabolizing enzymes through the activation of pregnane X receptor and constitutive androstane receptor. Drug Metab. Dispos

, 2020
Methadone (MD) is the most established substance abuse pharmacotherapy of choice for the management of heroin dependence. To date, drug-drug interactions involving MD have been characterized asymmetrically among existing reports, which describe how other
Haishan Li, Dr Hongbing Wang, Antonia H Tolson, Natalie D Eddington, Hongbing Wang   +4 more
core  

Constitutive androstane receptor (NR1I3; CAR) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Potent and Selective Human Constitutive Androstane Receptor Activator DL5055 Facilitates Cyclophosphamide-Based Chemotherapies. [PDF]

J Med Chem
Liang D, Li L, Ai Y, Li Z, Hedrich WD, Sakamuru S, Lynch C, Yu W, Watts-Ouattara I, Heyward S, Xia M, MacKerell AD, Wang H, Xue F.   +13 more
europepmc   +1 more source

Yes-Associated Protein Is Crucial for Constitutive Androstane Receptor-Driven Hepatocyte Proliferation But Not for Induction of Drug Metabolism Genes in Mice. [PDF]

Hepatology, 2021
Bhushan B, Molina L, Koral K, Stoops JW, Mars WM, Banerjee S, Orr A, Paranjpe S, Monga SP, Locker J, Michalopoulos GK.   +10 more
europepmc   +1 more source

Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling. [PDF]

World J Hepatol
Liu JJ, Mei HW, Jing YY, Li ZL, Wu SG, Yuan HX, Zhang XB.   +6 more
europepmc   +1 more source

Development of BODIPY FL SNS 032 as a Versatile Probe for Constitutive Androstane Receptor and Multiple Kinases. [PDF]

ACS Med Chem Lett
Lin W, Chen T.
europepmc   +1 more source

The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals. [PDF]

Arch Toxicol
Henderson CJ, McLaren AW, MacLeod AK, Lin D, Cameron AR, Chatham LR, Moggs J, Inesta-Vaquera F, Thomson JP, Meehan RR, Chakravarty P, Schwarz M, Wolf CR.   +12 more
europepmc   +1 more source

Boswellia carteri Birdw. Resin Extract Induces Phase-I Cytochrome P-450 Enzyme Gene Expressions in Human Hepatocarcinoma (Hep G2) Cells: In vitro and in silico Studies

Biologics: Targets & Therapy
Sahar S Alghamdi,1– 3 Hussah N Albahlal,1 Raghad Saleh Alajmi,1 Amani Alsharidah,4 Aljawharah Almogren,2 Rasha Suliman,5 Zeyad I Alehaideb1– 3 1King Saud Bin Abdulaziz University for Health Sciences (KSAU-HS), Riyadh, Saudi Arabia; 2King Abdullah ...
Alghamdi SS, Albahlal HN, Alajmi RS, Alsharidah A, Almogren A, Suliman R, Alehaideb ZI   +6 more
doaj  

Isoform-level expression of the constitutive androstane receptor (CAR or NR1I3) transcription factor better predicts the mRNA expression of the cytochrome P450s in human liver samples. [PDF]

Drug Metab Dispos
Collins JM, Wang D.
europepmc   +1 more source