Results 151 to 160 of about 45,599 (229)

Induction of cytochrome P450 via upregulation of CAR and PXR: a potential mechanism for altered florfenicol metabolism by macranthoidin B in vivo

Frontiers in Pharmacology
IntroductionMacranthoidin B (MB) is a primary active component of Flos Lonicerae. In Chinese veterinary clinics, Flos Lonicerae is frequently used in combination with florfenicol to prevent and treat infections in livestock and poultry.
Si-cong Li, Si-cong Li, Bin Wang, Bin Wang, Min Zhang, Min Zhang, Qin Yin, Zi-yi Yang, Zi-yi Yang, Xu-ting Li, Xu-ting Li, Ge Liang, Ge Liang   +12 more
doaj   +1 more source

Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver [PDF]

, 2017
Aberrant DNA methylation is a common feature of neoplastic lesions, and early detection of such changes may provide powerful mechanistic insights and biomarkers for carcinogenesis.
Hunter, Jennifer M., Lempiäinen, Harri, Meehan, Richard R., Moggs, Jonathan G., Müller, Arne, Terranova, Rémi, Thomson, John P.   +6 more
core  

Hibiscus sabdariffa Extract Protects HaCaT Cells against Phenanthrene-Induced Toxicity through the Regulation of Constitutive Androstane Receptor/Pregnane X Receptor Pathway. [PDF]

Nutrients, 2022
Malar DS, Prasanth MI, Verma K, Prasansuklab A, Tencomnao T.   +4 more
europepmc   +1 more source

Constitutive androstane receptor (NR1I3; CAR) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source

Lymphocyte-Specific Protein-1 Suppresses Xenobiotic-Induced Constitutive Androstane Receptor and Subsequent Yes-Associated Protein-Activated Hepatocyte Proliferation. [PDF]

Am J Pathol, 2022
Koral K, Bhushan B, Orr A, Stoops J, Bowen WC, Copeland MA, Locker J, Mars WM, Michalopoulos GK.   +8 more
europepmc   +1 more source

Direct activation of Constitutive Androstane Receptor by Phthalates [PDF]

Proceedings of the 2016 International Conference on Biological Engineering and Pharmacy (BEP 2016), 2017
Huiming CHEN, Hui HAN, Wenping XIE, Wenchao AI, Guolin SHEN, Haishan LI   +5 more
openaire   +1 more source

Effects of cytochrome P450 2B6 and constitutive androstane receptor genetic variation on Efavirenz plasma concentrations among HIV patients in Kenya. [PDF]

PLoS One, 2022
Ngayo MO, Oluka M, Kwena ZA, Bulimo WD, Okalebo FA.   +4 more
europepmc   +1 more source

Correction: MicroRNA-122 Down-Regulation Is Involved in Phenobarbital-Mediated Activation of the Constitutive Androstane Receptor

PLoS ONE, 2013
Ryota Shizu, Sawako Shindo, Takemi Yoshida, Satoshi Numazawa   +3 more
doaj   +3 more sources

Potent and Selective Human Constitutive Androstane Receptor Activator DL5055 Facilitates Cyclophosphamide-Based Chemotherapies. [PDF]

J Med Chem
Liang D, Li L, Ai Y, Li Z, Hedrich WD, Sakamuru S, Lynch C, Yu W, Watts-Ouattara I, Heyward S, Xia M, MacKerell AD, Wang H, Xue F.   +13 more
europepmc   +1 more source

Yinchenhao decoction alleviates obstructive jaundice liver injury by modulating epidermal growth factor receptor and constitutive androstane receptor signaling. [PDF]

World J Hepatol
Liu JJ, Mei HW, Jing YY, Li ZL, Wu SG, Yuan HX, Zhang XB.   +6 more
europepmc   +1 more source