Results 201 to 210 of about 11,039 (305)

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Evaluating celebrity influence on brand attention, emotion, and memory. [PDF]

Sci Rep
Michael N, Ramsøy TZ, Michael I.
europepmc   +1 more source

Synergistic Stabilization of Potassium Metal Anodes Through Orange‐Peel Elimination and Robust Solid–Electrolyte Interphase Formation

Advanced Science, EarlyView.
Synergistic control of surface uniformity and solid–electrolyte interphase robustness regulates potassium deposition, suppressing dendritic growth and enabling uniform, dense potassium plating. This combined strategy promotes stable interfacial chemistry and homogeneous electric‐field distribution, leading to enhanced reversibility and long‐term ...
Pan He, Yupei Han, Yundong Zhou, Ruhan He, Rui Xu, Yunlong Zhao, Junjun Wang, Wanjun Ren, Matthew Hopper, Qinyou An, Denys Makarov, Ian S. Gilmore, Liqiang Mai, Yang Xu   +13 more
wiley   +1 more source

Transforming data to delight: AI-led campaign personalization shapes digital natives' intention to accept over a TAM-VAM approach. [PDF]

Front Artif Intell
Durgha Devi L, Arumugam T.
europepmc   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

Advanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz, Saurabh Upadhyay, Renjie Zhu, Hongliang Duan, Moustafa T. Gabr   +4 more
wiley   +1 more source

Digital Marketing Tactics, Non-Compliance With the International Code of Marketing of Breastmilk Substitutes and Legal Breaches of Code-Based Legislation by the Commercial Milk Formula Industry in Central America and the Caribbean. [PDF]

Matern Child Nutr
Mazariegos M, Paz B, Álvarez L, De León JR.   +3 more
europepmc   +1 more source

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source

Agricultural products: A study on the impact of social presence on customer engagement in livestream marketing. [PDF]

PLoS One
Sun Q, Cao J, Guo C, Shi Y.
europepmc   +1 more source

Entropy Decoding the Fundamental Law of Phase Competition in Glass Formation

Advanced Science, EarlyView.
We validate the integration of intermetallic and eutectic phases as initial phases for composition design. The phase competition mechanism in glass formation is quantitatively clarified based on the melting entropy of competing phases. Glass‐forming ability is modulated by tuning phase competition via the melting entropy of initial phases.
Benke Huo, Zhengqing Cai, Bingtao Wang, Zhenqiang Song, Shi‐Dong Feng, Zijing Li, Xingjun Liu, Li‐Min Wang   +7 more
wiley   +1 more source

Predicting Consumer Adoption of Luxury Products via Instagram Marketing: A Machine Learning Approach. [PDF]

F1000Res
Nallasivam A, S GK, Jagadeeswari IU, Desai G, Bandhu D.   +4 more
europepmc   +1 more source