Results 21 to 30 of about 75,941 (270)
Active force maintains the stability of a contractile ring
The European Physical Journal E, 2017 We investigate a system of sufficiently dense polar actin filaments considered rigid and cross-linked by dimer myosin II protein within the contractile ring.
Stanard Mebwe Pachong +1 more
core +3 more sources
Redundant mechanisms recruit actin into the contractile ring in silkworm spermatocytes. [PDF]
PLoS Biology, 2008 Cytokinesis is powered by the contraction of actomyosin filaments within the newly assembled contractile ring. Microtubules are a spindle component that is essential for the induction of cytokinesis. This induction could use central spindle and/or astral
Wei Chen +3 more
doaj +2 more sources
Mechanistic insights into the anchorage of the contractile ring by anillin and Mid1. [PDF]
Dev Cell, 2015 SummaryAnillins and Mid1 are scaffold proteins that play key roles in anchorage of the contractile ring at the cell equator during cytokinesis in animals and fungi, respectively. Here, we report crystal structures and functional analysis of human anillin
Sun L +7 more
europepmc +5 more sources
Contractile ring composition dictates kinetics of in silico contractility. [PDF]
Biophys J, 2023 Constriction kinetics of the cytokinetic ring are expected to depend on dynamic adjustment of contractile ring composition, but the impact of ring component abundance dynamics on ring constriction is understudied. Computational models generally assume that contractile networks maintain constant total amounts of components, which is not always true.
Cortes DB +3 more
europepmc +3 more sources
An essential contractile ring protein controls cell division in Plasmodium falciparum [PDF]
Nature Communications, 2019 Schizogony is essential for blood stage infection of Plasmodium parasites and produces several daughter cells. Here, Rudlaff et al. identify PfCINCH and interacting proteins as essential components of the basal complex required to establish daughter cell
Rachel M. Rudlaff +3 more
doaj +2 more sources
Robust gap repair in the contractile ring ensures timely completion of cytokinesis. [PDF]
J Cell Biol, 2016 Cytokinesis in animal cells requires the constriction of an actomyosin contractile ring, whose architecture and mechanism remain poorly understood. We use laser microsurgery to explore the biophysical properties of constricting rings in Caenorhabditis ...
Silva AM +8 more
europepmc +4 more sources
Curr Biol, 2011 What is the contractile ring? During cell division, the contractile ring generates the constricting force to separate one cell into two cells. Formed during cytokinesis, the last step of cell division, the contractile ring is composed of filamentous actin (F-actin) and the motor protein myosin-2, along with additional structural and regulatory proteins.
Miller AL.
europepmc +4 more sources
Dynamics and Stability of the Contractile Actomyosin Ring in the Cell [PDF]
Physical Review Letters, 2022 Contraction of the cytokinetic ring during cell division leads to physical partitioning of a eukaryotic cell into two daughter cells. This involves flows of actin filaments and myosin motors in the growing membrane interface at the mid-plane of the dividing cell.
Mainak Chatterjee +3 more
openaire +3 more sources
Current Biology, 2003 What is it? The contractile ring is a ring-shaped structure located just beneath the plasma membrane at the future division site in many, though not all, eukaryotic cell types. Composed of actin, myosin and many other proteins, it assembles in anaphase and contracts as cells divide. The contractile ring is responsible for cytokinesis in many eukaryotic
Chang, Fred, Burgess, David
openaire +2 more sources
Reconstitution of contractile actomyosin rings in vesicles [PDF]
Nature Communications, 2020 Abstract One of the grand challenges of bottom-up synthetic biology is the development of minimal machineries for cell division. The mechanical transformation of large-scale compartments, such as Giant Unilamellar Vesicles (GUVs), requires the geometry-specific coordination of active elements, several orders of magnitude larger than ...
Thomas Litschel +8 more
openaire +5 more sources