Mechanism of cytokinetic contractile ring constriction in fission yeast. [PDF]
Dev Cell, 2014 Cytokinesis involves constriction of a contractile actomyosin ring. The mechanisms generating ring tension and setting the constriction rate remain unknown because the organization of the ring is poorly characterized, its tension was rarely measured, and constriction is coupled to other processes.
Stachowiak MR +6 more
europepmc +4 more sources
Formation and function of the polar body contractile ring in Spisula
Developmental Biology, 2004 Initial studies suggested that spatial organization of the putative polar body contractile ring was determined by the peripheral aster in Spisula [Biol. Bull. 205 (2003) 192]. Here we report detailed supporting observations, including testing of aster and ring function with inhibitors.
Pielak, Rafal M +2 more
exaly +3 more sources
Animal Cell Cytokinesis: The Rho-Dependent Actomyosin-Anilloseptin Contractile Ring as a Membrane Microdomain Gathering, Compressing, and Sorting Machine [PDF]
Frontiers in Cell and Developmental Biology, 2020 Gilles Hickson, Sabrya Carim
exaly +2 more sources
Dynamics and Stability of the Contractile Actomyosin Ring in the Cell [PDF]
Physical Review Letters, 2022 Contraction of the cytokinetic ring during cell division leads to physical partitioning of a eukaryotic cell into two daughter cells. This involves flows of actin filaments and myosin motors in the growing membrane interface at the mid-plane of the dividing cell.
Mainak Chatterjee +3 more
openaire +3 more sources
Current Biology, 2003 What is it? The contractile ring is a ring-shaped structure located just beneath the plasma membrane at the future division site in many, though not all, eukaryotic cell types. Composed of actin, myosin and many other proteins, it assembles in anaphase and contracts as cells divide. The contractile ring is responsible for cytokinesis in many eukaryotic
Chang, Fred, Burgess, David
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Molecular Model of the Contractile Ring [PDF]
Physical Review Letters, 2005 PACS numbers: 87.16.Ka, 87.16.Ac http://www.ncbi.nlm.nih.gov/pubmed/16197254 http://www.weizmann.ac.il/complex/tlusty/papers/PhysRevLett2005 ...
Biron, D +3 more
openaire +4 more sources
Reconstitution of contractile actomyosin rings in vesicles [PDF]
Nature Communications, 2020 Abstract One of the grand challenges of bottom-up synthetic biology is the development of minimal machineries for cell division. The mechanical transformation of large-scale compartments, such as Giant Unilamellar Vesicles (GUVs), requires the geometry-specific coordination of active elements, several orders of magnitude larger than ...
Thomas Litschel +8 more
openaire +5 more sources
Anillin propels myosin-independent constriction of actin rings
Nature Communications, 2021 Cytokinetic ring constriction during cell division requires actin but curiously is independent of myosin in many organisms. Here, the authors show that anillin, a protein enriched in the contractile ring, is a non-motor actin crosslinker that generates ...
Ondřej Kučera +8 more
doaj +1 more source
Redistribution of actin during assembly and reassembly of the contractile ring in grasshopper spermatocytes. [PDF]
PLoS ONE, 2009 Cytokinesis in animal cells requires the assembly of an actomyosin contractile ring to cleave the cell. The ring is highly dynamic; it assembles and disassembles during each cell cleavage, resulting in the recurrent redistribution of actin.
G Bradley Alsop +4 more
doaj +1 more source
The integrity of the cytokinesis machinery under stress conditions requires the glucan synthase Bgs1p and its regulator Cfh3p. [PDF]
PLoS ONE, 2012 In yeast, cytokinesis requires coordination between nuclear division, acto-myosin ring contraction, and septum synthesis. We studied the role of the Schizosaccharomyces pombe Bgs1p and Cfh3p proteins during cytokinesis under stress conditions.
Mohammad Reza Sharifmoghadam +6 more
doaj +1 more source