Results 41 to 50 of about 74,573 (237)
Redundant mechanisms recruit actin into the contractile ring in silkworm spermatocytes. [PDF]
PLoS Biology, 2008 Cytokinesis is powered by the contraction of actomyosin filaments within the newly assembled contractile ring. Microtubules are a spindle component that is essential for the induction of cytokinesis. This induction could use central spindle and/or astral
Wei Chen +3 more
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Kinetics of Myosin Node Aggregation into a Contractile Ring [PDF]
Physical Review Letters, 2010 We study a stochastic aggregation model for the assembly of the contractile ring from a broad band of nodes during cytokinesis in fission yeast. We found that bands of nodes condense into rings when the range of node interactions is larger than the width of the band. Wide bands are unstable to clump formation due to Poisson density fluctuations.
Nikola, Ojkic, Dimitrios, Vavylonis
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Haematologica, 2017 The formin protein mDia2 plays a critical role in a number of cellular processes through its ability to promote nucleation and elongation of actin filaments. In erythroblasts, this includes control of cytokinesis and enucleation by regulating contractile
Xuehui Li +6 more
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Contractile ring formation [PDF]
The Journal of Cell Biology, 2006 ![Graphic][1] A broad band of nodes is the precursor to a cytokinetic ring. During cytokinesis the actin–myosin contractile ring forms between two daughter cells, pinching them apart. On page [391][2], Wu et al.
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Aurora B but not rho/MLCK signaling is required for localization of diphosphorylated myosin II regulatory light chain to the midzone in cytokinesis. [PDF]
PLoS ONE, 2013 Non-muscle myosin II is stimulated by monophosphorylation of its regulatory light chain (MRLC) at Ser19 (1P-MRLC). MRLC diphosphorylation at Thr18/Ser19 (2P-MRLC) further enhances the ATPase activity of myosin II.
Tomo Kondo +5 more
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Reconstitution of Contractile FtsZ Rings in Liposomes
Science, 2008 FtsZ is a tubulin homolog and the major cytoskeletal protein in bacterial cell division. It assembles into the Z ring, which contains FtsZ and a dozen other division proteins, and constricts to divide the cell. We have constructed a membrane-targeted FtsZ (FtsZ-mts) by splicing an amphipathic helix to its C terminus.
Masaki, Osawa +2 more
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Septin filament compaction into rings requires the anillin Mid2 and contractile ring constriction
Cell Reports, 2022 Septin filaments assemble into high-order molecular structures that associate with membranes, acting as diffusion barriers and scaffold proteins crucial for many cellular processes. How septin filaments organize in such structures is still not understood.
Arbizzani, Federica +6 more
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The Role of the Contractile Ring during Cytokinesis [PDF]
Biophysical Journal, 2012 Cytokinesis in animals and fungi involves constriction of an actomyosin contractile ring, but the constriction mechanisms and the role of the ring are not established. The constriction rate could be determined only by the properties and internal dynamics of the ring itself (a “dynamically autonomous” mechanism) as suggested by recent experiments on C ...
Stachowiak, Matthew R. +3 more
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eLife, 2019 We previously discovered that competition between fission yeast actin binding proteins (ABPs) for binding F-actin facilitates their sorting to different cellular networks.
Jenna R Christensen +7 more
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Quantitative analysis of cytokinesis in situ during C. elegans postembryonic development. [PDF]
PLoS ONE, 2014 The physical separation of a cell into two daughter cells during cytokinesis requires cell-intrinsic shape changes driven by a contractile ring. However, in vivo, cells interact with their environment, which includes other cells.
Karine G Bourdages +4 more
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