The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Experimental investigation of the performance of different modulation techniques under controlled FSO turbulence channel [PDF]
This paper experimentally investigates and compares the performance of the free space optics system employing three different modulation schemes, on-off keying (OOK) with nonreturn- to-zero (NRZ) and return-to-zero (RZ) and the binary phase shift keying (
Adebanjo, Olusegun +5 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Gas diffusion liquid storage bag and method of use for storing blood [PDF]
The shelf life of stored whole blood may be doubled by adding a buffer which maintains a desired pH level. However, this buffer causes the generation of CO2 which, if not removed at a controlled rate, causes the pH value of the blood to decrease, which ...
Bank, H., Cleland, E. L.
core +1 more source
Effect of molecular relaxation on the propagation of sonic booms through a stratified atmosphere [PDF]
Nonlinear acoustic wave propagation through a stratified atmosphere is considered. The initial signal is taken to be an isolated N-wave, which is the disturbance that is generated some distance away from a supersonic body in horizontal flight. The effect
Blythe +19 more
core +1 more source
Controlled atmosphere and dynamic controlled atmosphere for Fuzzy logic-based banana storage
The insertion of New Information and Communication Technologies is increasingly present in the most diverse fields of knowledge, among them agriculture. This insertion results in what is called precision agriculture. Postharvest of bananas requires the application of new technologies to increase storage time and reduce losses.
Bruno Pansera-Espíndola +2 more
openaire +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Arc spray fabrication of metal matrix composite monotape [PDF]
Arc metal spraying is used to spray liquid metal onto an array of high strength fibers that were previously wound onto a large drum contained inside a controlled atmosphere chamber.
Westfall, L. J.
core +1 more source
Discussion On Device Structures And Hermetic Encapsulation For SiOx Random Access Memory Operation In Air [PDF]
An edge-free structure and hermetic encapsulation technique are presented that enable SiOx-based resistive random-access memory (RRAM) operation in air. A controlled etch study indicates that the switching filament is close to the SiOx surface in devices
Chang, Yao-Feng +6 more
core +1 more source

