Results 31 to 40 of about 16,152 (159)

A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi. [PDF]

, 2017
Capitalizing on CRISPR/Cas9 gene-editing techniques and super-resolution nanoscopy, we explore the role of the small GTPase ARF1 in mediating transport steps at the Golgi.
Baddeley, David, Bewersdorf, Joerg, Bottanelli, Francesca, Erdmann, Roman S, Ernst, Andreas M, Kilian, Nicole, Kromann, Emil B, Lessard, Mark D, Rivera-Molina, Felix, Rothman, James E, Schepartz, Alanna, Schroeder, Lena K, Toomre, Derek   +12 more
core   +2 more sources

Sorting by COP I-coated vesicles under interphase and mitotic conditions

Journal of Cell Biology, 1996
COP I-coated vesicles were analyzed for their content of resident Golgi enzymes (N-acetylgalactosaminyltransferase; N- acetylglucosaminyltransferase I; mannosidase II; galactosyltransferase), cargo (rat serum albumin; polyimmunoglobulin receptor), and ...
Birte Stinnichsen, Rose Watson, Henrik Clausen, T. Misteli, G. Warren   +4 more
semanticscholar   +1 more source

Subcellular trafficking of the Arabidopsis auxin influx carrier AUX1 uses a novel pathway distinct from PIN1 [PDF]

, 2006
The directional flow of the plant hormone auxin mediates multiple developmental processes, including patterning and tropisms. Apical and basal plasma membrane localization of AUXIN-RESISTANT1 (AUX1) and PIN-FORMED1 (PIN1) auxin transport components ...
Bennett, Malcolm, Dhonukshe, Pankaj, Friml, Jiri, Kleine-Vehn, Jürgen, Swarup, Ranjan   +4 more
core   +2 more sources

Intracellular Trafficking and Secretion of Adiponectin Is Dependent on GGA-coated Vesicles*

Journal of Biological Chemistry, 2006
Adiponectin (Acrp30) is an insulin-sensitizing hormone produced and secreted exclusively by adipose tissue. Confocal fluorescent microscopy demonstrated the colocalization of adiponectin with the Golgi membrane markers p115, β-COP, and the trans-Golgi ...
Linglin Xie, D. Boyle, Daniel Sanford, P. Scherer, J. Pessin, S. Mora   +5 more
semanticscholar   +2 more sources

A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells

Life Science Alliance, 2020
The paralogous COPI coat subunit γ1-COP plays a unique role in promoting neurite outgrowth during the neuronal differentiation of mouse pluripotent cells.
Manu Jain Goyal, Xiyan Zhao, Mariyana Bozhinova, Karla Andrade-López, Cecilia de Heus, Sandra Schulze-Dramac, Michaela Müller-McNicoll, J. Klumperman, J. Béthune   +8 more
semanticscholar   +1 more source

COPI mediates recycling of an exocytic SNARE by recognition of a ubiquitin sorting signal [PDF]

, 2017
The COPI coat forms transport vesicles from the Golgi complex and plays a poorly defined role in endocytic trafficking. Here we show that COPI binds K63-linked polyubiquitin and this interaction is crucial for trafficking of a ubiquitinated yeast SNARE ...
Diab, Nicholas S, Erlinger, Samuel J, Frazier, Meredith N, Graham, Todd R, Hankins, Hannah M, Jackson, Lauren P, MacDonald, Chris, MacGurn, Jason A, Piper, Robert C, Xu, Peng   +9 more
core   +2 more sources

Annexin-A5 assembled into two-dimensional arrays promotes cell membrane repair [PDF]

, 2011
Eukaryotic cells possess a universal repair machinery that ensures rapid resealing of plasma membrane disruptions. Before resealing, the torn membrane is submitted to considerable tension, which functions to expand the disruption.
A Brisson, A Brisson, AK McNeil, B Brachvogel, B Brachvogel, B Brachvogel, B Jeppesen, C Cai, C Cai, C Pigault, C Vénien-Bryan, CE Creutz, CJ Merrifield, D Bansal, D Bansal, D Voges, EB Babiychuk, F D'Acquisto, F Oling, F Oling, G Mosser, GQ Bi, HA Andree, I Reviakine, J Liu, JH Rand, K Balasubramanian, K Monastyrskaya, L Glover, M Menke, M Rodahl, MA Kaetzel, MA Swairjo, MP Sheetz, NJ Lennon, NO Concha, NO Concha, O Lambert, O Saurel, PL McNeil, PL McNeil, PL McNeil, Q Ling, R Bérat, R Huber, R Huber, R Langen, R Richter, RA Steinhardt, RP Richter, S Yasuda, SE Moss, T Skrahina, T Togo, T Yeung, V Gerke, Y Mo   +56 more
core   +2 more sources

The Proteasomal Deubiquitinating Enzyme PSMD14 Regulates Macroautophagy by Controlling Golgi-to-ER Retrograde Transport [PDF]

, 2020
Ubiquitination regulates several biological processes, however the role of specific members of the ubiquitinome on intracellular membrane trafficking is not yet fully understood.
Arias-Muñoz, Eloisa, Bandau, Susanne, Burgos, Patricia V., Bustamante, Hianara A., Cancino, Jorge, Cerda-Troncoso, Cristóbal, Cereceda, Karina, Cheuquemilla, Yorka, González, Alexis E., Hay, Ronald T., Hernández, Sergio, Kausel, Gudrun, Kerr, Bredford, Mardones, Gonzalo A., Rojas-Fernandez, Alejandro, Soza, Andrea, Valenzuela, Guillermo E.   +16 more
core   +2 more sources

100-kD proteins of Golgi- and trans-Golgi network-associated coated vesicles have related but distinct membrane binding properties

Journal of Cell Biology, 1992
The 100-110-kD proteins (alpha-, beta-, beta'-, and gamma-adaptins) of clathrin-coated vesicles and the 110-kD protein (beta-COP) of the nonclathrin-coated vesicles that mediate constitutive transport through the Golgi have homologous protein sequences ...
Darren H. Wong, Frances M. Brodsky
semanticscholar   +1 more source

"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]

, 2007
Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
core   +1 more source