Results 51 to 60 of about 28,140 (260)
Lysophospholipids Facilitate COPII Vesicle Formation [PDF]
Current Biology, 2018 Coat protein complex II (COPII) proteins form vesicles from the endoplasmic reticulum to export cargo molecules to the Golgi apparatus. Among the many proteins involved in this process, Sec12 is a key regulator, functioning as the guanosine diphosphate (GDP) exchange factor for Sar1p, the small guanosine triphosphatase (GTPase) that initiates COPII ...
Melero Carrillo, Alejandro +7 more
openaire +3 more sources
NEFROPATIILE TOXICE ÎN INTOXICAŢIILE ACUTE LA COPIL ŞI ADOLESCENT – PREVALENŢĂ, CAUZE ŞI FACTORI DE RISC [PDF]
Romanian Journal of Pediatrics, 2014 Obiective. Incidenţa şi prevalenţa reală a afectării renale în cadrul intoxicaţiilor copilului nu este pe deplin cunoscută, modifi cările funcţionale şi structurale renale cauzate de nefrotoxine sunt nespecifi ce şi de multe ori etiologia toxică este ...
Alexandru-Ioan Ulmeanu +2 more
doaj +1 more source
Cholesterol impairment contributes to neuroserpin aggregation [PDF]
, 2017 Intraneural accumulation of misfolded proteins is a common feature of several neurodegenerative pathologies including Alzheimer's and Parkinson's diseases, and Familial Encephalopathy with Neuroserpin Inclusion Bodies (FENIB). FENIB is a rare disease due
Costantini, Giulio +5 more
core +2 more sources
Mechanical strain stimulates COPII‐dependent secretory trafficking via Rac1
EMBO Journal, 2022 Cells are constantly exposed to various chemical and physical stimuli. While much has been learned about the biochemical factors that regulate secretory trafficking from the endoplasmic reticulum (ER), much less is known about whether and how this ...
Santosh Phuyal +15 more
semanticscholar +1 more source
The role of traction in membrane curvature generation. [PDF]
, 2018 Curvature of biological membranes can be generated by a variety of molecular mechanisms including protein scaffolding, compositional heterogeneity, and cytoskeletal forces.
Alimohamadi, H +4 more
core +1 more source
A Study on the Origin of Peroxisomes: Possibility of Actinobacteria Symbiosis [PDF]
, 2008 The origin of peroxisomes as having developed from the endoplasmic reticulum (ER) was proposed on the basis of the similarity between some peroxisomal proteins and ER proteins, and the localization of some peroxisomal proteins on the ER.
Duhita Narendra +5 more
core +2 more sources
TRAPPC9 mediates the interaction between p150 and COPII vesicles at the target membrane. [PDF]
PLoS ONE, 2012 The transport of endoplasmic reticulum (ER)-derived COPII vesicles toward the ER-Golgi intermediate compartment (ERGIC) requires cytoplasmic dynein and is dependent on microtubules. p150(Glued), a subunit of dynactin, has been implicated in the transport
Min Zong +7 more
doaj +1 more source
Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale, 2021 Pe parcursul a 40 de ani în clinica „Chirurgia tumorilor regiunii capului și gâtului” a Institutului Oncologic din Republica Moldova au fost tratați 18549 de pacienți cu patologii nodulare tiroidiene, dintre care 1078 au fost copii.
Andrei Ţîbîrnă +2 more
doaj +1 more source
Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking. [PDF]
, 2020 Collagen is the most abundant protein in animals. Its dysregulation contributes to aging and many human disorders, including pathological tissue fibrosis in major organs.
Bai, Meirong +12 more
core +1 more source