Results 81 to 90 of about 28,140 (260)

SINDROMUL MÜNCHAUSEN PRIN TRANSFER – O PROBLEMĂ REALĂ PEDIATRICĂ? [PDF]

Romanian Journal of Pediatrics, 2015
Sindromul Münchausen (SM) şi Münchausen prin transfer (SMPT) aparţin afecţiunilor numite „Factitious disorder şi reprezintă tulburări mentale severe care au ca „scop“ situaţia de a deveni pacient respectiv de a „fabrica“ o boală unei alte persoane, afl ...
Daniela Păcurar, Maria Runcan, Anca Popescu, Gabriela Leşanu, Dumitru Orăşeanu   +4 more
doaj   +1 more source

Tailored assemblies of COPII proteins in secretion. [PDF]

J Cell Biol
Vivek Malhotra discusses our emerging understanding of the roles of COPII in mediating the export of diverse cargoes from the ER.
Malhotra V.
europepmc   +2 more sources

The p24-family and COPII subunit SEC24C facilitate the clearance of alpha1-antitrypsin Z from the endoplasmic reticulum to lysosomes

Molecular Biology of the Cell
A subpopulation of the alpha-1-antitrypsin misfolding Z mutant (ATZ) is cleared from the endoplasmic reticulum (ER) via an ER-to-lysosome-associated degradation (ERLAD) pathway. Here, we report that the COPII subunit SEC24C and the p24-family of proteins
Benjamin S Roberts, Debashree Mitra, Sudhanshu Abishek, Richa Beher, Prasanna Satpute-Krishnan   +4 more
semanticscholar   +1 more source

COPII Sec23 proteins form isoform-specific endoplasmic reticulum exit sites with differential effects on polarized growth.

The Plant Cell, 2021
COPII, a coat protein complex that forms vesicles on the endoplasmic reticulum (ER), mediates trafficking to the Golgi. While metazoans have few genes encoding each COPII component, plants have expanded these gene families, leading to the hypothesis that
Mingqin Chang, Shu-Zon Wu, Samantha E Ryken, Jacquelyn E O'Sullivan, M. Bezanilla   +4 more
semanticscholar   +1 more source

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

VIEW, EarlyView.
ABSTRACT This study investigated the function of epididymal extracellular vesicles (EVs) in overcoming sperm post‐testicular modification deficiencies. Although EVs derived from the epididymis play a crucial role in intercellular communication and molecular exchange, there is limited research addressing how EVs released by in vitro cultured epididymal ...
Long Li, Haonan Zhao, Yibo Li, Qixin Xu, Yang Zi, Tingting Chu, Heran Cao, Shujuan Liu, Zifang Wu, Huanqiang Zhao, Wuzi Dong   +10 more
wiley   +1 more source

INDICELE INTIMĂ MEDIE CAROTIDIAN LA COPIII OBEZI NĂSCUŢI CU GREUTATE MICĂ PENTRU VÂRSTA GESTAŢIONALĂ VERSUS CEI NĂSCUŢI CU GREUTATE NORMALĂ PENTRU VÂRSTA GESTAŢIONALĂ [PDF]

Romanian Journal of Pediatrics, 2014
Indicele intimǎ medie carotidian (IMc) este un cunoscut marker subclinic pentru aterosclerozǎ. Fenomenul de recuperare nutriţionalǎ la copiii nǎscuţi mici pentru vârsta gestaţionalǎ (SGA) a fost asociat cu obezitate precoce şi cu riscul dezvoltǎrii ...
Ramona Stroescu, Ioana Micle, Teofana Bizerea, Monica Mărăzan, Maria Puiu, Gabriela Doroş, Otilia Mărginean   +6 more
doaj   +1 more source

COPII mitigates ER stress by promoting formation of ER whorls

Cell Research, 2020
Cells mitigate ER stress through the unfolded protein response (UPR). Here, we report formation of ER whorls as an effector mechanism of the ER stress response.
Fang Xu, Wanqing Du, Qin Zou, Yuting Wang, Xin Zhang, Xudong Xing, Ying Li, Dachuan Zhang, Huimin Wang, Wenhao Zhang, Xinyao Hu, Xin Liu, Xiaoling Liu, Shaojin Zhang, Jinqiang Yu, Jianhuo Fang, Fajin Li, Ying Zhou, T. Yue, Na Mi, Haiteng Deng, Peng Zou, Xiaowei Chen, Xuerui Yang, Li Yu   +24 more
semanticscholar   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

Andrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre, Ross C. Anderson, Teresa Zariñán, Rubén Gutiérrez‐Sagal, Eduardo Jardón‐Valadez, Claire L. Newton   +5 more
wiley   +1 more source

A Minimum-Labeling Approach for Reconstructing Protein Networks across Multiple Conditions [PDF]

, 2013
The sheer amounts of biological data that are generated in recent years have driven the development of network analysis tools to facilitate the interpretation and representation of these data.
D. Beisser, E. Lotem, H. Farhan, J. Simpson, M. Hamasaki, N. Ishihara, N. Mizushima, O. Engelhardt, P. Watson, S. Shapira   +9 more
core   +3 more sources

Structure of the complete, membrane-assembled COPII coat reveals a complex interaction network

Nature Communications, 2020
COPII mediates Endoplasmic Reticulum to Golgi trafficking of thousands of cargoes. Five essential proteins assemble into a two-layer architecture, with the inner layer thought to regulate coat assembly and cargo recruitment, and the outer coat forming ...
J. Hutchings, Viktoriya G Stancheva, N. Brown, A. Cheung, E. Miller, G. Zanetti   +5 more
semanticscholar   +1 more source