Results 181 to 190 of about 15,919 (216)
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Bioavailability of water-soluble CoQ10 in beagle dogs
Journal of Pharmaceutical and Biomedical Analysis, 2008The bioavailability of a novel water-soluble inclusion complex of CoQ10, prepared in our laboratory was determined and compared with the bioavailability of commercially available oil-based form of CoQ10. Experimental work consisted of single dose comparative bioavailability study on seven beagle dogs, with a 14-day washout period between treatments ...
Mirko, Prosek +6 more
exaly +3 more sources
Archives of Biochemistry and Biophysics, 2019
Coenzyme Q10 (CoQ10) is an essential factor in the mitochondrial respiratory chain and is closely associated with ATP production in humans. It is known that orally administered CoQ10 in humans is rapidly reduced, and most is detected as a reduced form, ubiquinol-10 (CoQ10H2), in serum.
Takayuki, Takahashi +2 more
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Coenzyme Q10 (CoQ10) is an essential factor in the mitochondrial respiratory chain and is closely associated with ATP production in humans. It is known that orally administered CoQ10 in humans is rapidly reduced, and most is detected as a reduced form, ubiquinol-10 (CoQ10H2), in serum.
Takayuki, Takahashi +2 more
openaire +2 more sources
The role of CoQ10 in embryonic development
Journal of Assisted Reproduction and GeneticsCoenzyme Q10 (CoQ10) is a natural component widely present in the inner membrane of mitochondria. CoQ10 functions as a key cofactor for adenosine triphosphate (ATP) production and exhibits antioxidant properties in vivo. Mitochondria, as the energy supply center of cells, play a crucial role in germ cell maturation and embryonic development, a ...
Xueke He +6 more
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Formation of CoQ10 reduced form by mixing CoQ10 oxidized form γCD complex and vitamin C in powder
Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2010We have already reported the enhancement of the stability and bioavailability of coenzyme Q10 (CoQ10) oxidized form by γ-cyclodextrin (γCD) complexation. In a series of the studies, we investigated an easy and economical conversion of CoQ10 oxidized form to its reduced form in complex powder, using inexpensive vitamin C (VC) as the reductant.
Yukiko Uekaji +7 more
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Skin penetration of CoQ10 in the rat.
International journal of tissue reactions, 1988Skin penetration of coenzyme Q10 (CoQ10) was investigated after topical treatment in the rat. The drug was suspended in olive oil and administered at two different concentrations. Coenzyme levels were found to be directly related to the concentrations employed and the contact time.
GIOVANNINI, LUCA +5 more
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Benefits of CoQ10 supplementation in patients with SRNS due to primary CoQ10 deficiency
Nature Reviews Nephrology, 2022openaire +2 more sources
Breast cancer treatment with coenzyme Q10 (CoQ10)
Multidisciplinary ReviewsCoenzyme Q10 (CoQ10) was identified in the late 1950s, and its potential role in cancer therapy appeared in the early 1960s when decreasing CoQ10 levels were found in some cancer patients. Breast cancer is a serious global health issue, and novel treatments are being developed. Its treatment is being investigated.
Pratiksha V. Shende +2 more
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The polar oxy-metabolome reveals the 4-hydroxymandelate CoQ10 synthesis pathway
Nature, 2021Keisuke Yamamoto +2 more
exaly
UBIAD1 and CoQ10 protect melanoma cells from lipid peroxidation-mediated cell death
Redox Biology, 2022Manuela Simonato +2 more
exaly
Chapter 34 - Primary Cerebellar CoQ10 Deficiency
2016Coenzyme Q10 (CoQ10), also known as ubiquinone, is an endogenously synthesized lipid that transfers electrons from complexes I (NADH-ubiquinone oxidoreductase) and II (succinate-ubiquinone oxidoreductase) and from the oxidation of fatty acids and branched-chain amino acids (via flavin-linked dehydrogenases) to complex III (succinate-cytochrome c ...
Quinzii, Catarina +2 more
openaire +1 more source