Results 121 to 130 of about 5,838 (160)

Immunoglobulin G N-glycosylation remodeling in viral infections: immunomodulatory roles and potential biomarker implications. [PDF]

Front Immunol
Yan R, Wang C, Zhao X, Wang Y, Liu M, Shi X, Chen H, Li D.   +7 more
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N-glycomics profiling reveals alteration of fucosylation in early acute ischemic stroke from mouse brain tissue to human serum. [PDF]

Clin Proteomics
Wu Y, Hu L, Huang J, Zhong Y, Li K, Qiu Z, Su L, Zhang Y, Liu W.   +8 more
europepmc   +1 more source

Core fucosylation regulates EGF receptor-mediated intracellular signaling

Core fucosylation regulates EGF receptor-mediated intracellular signaling
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High Throughput Screening Tools to Probe and Inhibit Core Fucosylation

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A fluorogenic probe for core-fucosylated glycan-preferred ENGase

Carbohydrate Research, 2023
A fluorescence-quenching-based assay system to determine the hydrolytic activity of endo-β-N-acetylglucosaminidases (ENGases), which act on the innermost N-acetylglucosamine (GlcNAc) residue of the chitobiose segment of core-fucosylated N-glycans, was constructed using a dual-labeled fluorescent probe with a hexasaccharide structure.
Nozomi Ishii, Hiroshi Muto, Mitsuo Nagata, Kanae Sano, Itsuki Sato, Kenta Iino, Yuji Matsuzaki, Toshihiko Katoh, Kenji Yamamoto, Ichiro Matsuo   +9 more
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Modular Synthesis of Core Fucosylated N‐Glycans

European Journal of Organic Chemistry, 2012
AbstractA modular synthesis of complex‐type N‐glycans containing the core fucosyl motif was optimized. The core trisaccharide building block was protected by a methoxyphenyl group for convenient core fucosylation. The trisaccharide was obtained on a large scale from the glycosylation of the corresponding chitobiosyl azide with a glucosyl donor followed
Dimitri Ott, Joachim Seifert, Ingo Prahl, Mathäus Niemietz, Joanna Hoffman, Janna Guder, Manuel Mönnich, Carlo Unverzagt   +7 more
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Identification of Core-Fucosylated Glycoproteome in Human Plasma

2017
The core-fucosylated (CF) glycoproteins are widely distributed in mammalian tissues and regulated under pathological conditions, especially in cancer progression. The Food and Drug Administration (FDA) has approved the core-fucosylated α-fetoprotein as a biomarker for the early diagnosis of hepatocellular carcinoma (HCC). An approach for identifying CF
Qichen, Cao, Qing, Zhao, Xiaohong, Qian, Wantao, Ying   +3 more
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Inhibition of core fucosylation limits progression of diabetic kidney disease

Biochemical and Biophysical Research Communications, 2019
FUT8-mediated core fucosylation, which transfers a fucose residue from GDP-fucose to core-GlcNAc of the N-linked type glycoproteins, is crucial for signaling receptors function. Core fucosylation is involved in various biological processes such as cell proliferation, apoptosis, differentiation and immune regulation.
Ming, Fang, Le, Kang, Xiaolang, Wang, Xianan, Guo, Weidong, Wang, Biaojie, Qin, Xiangning, Du, Qingzhu, Tang, Hongli, Lin   +8 more
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Inhibiting core fucosylation attenuates glucose-induced peritoneal fibrosis in rats

Kidney International, 2018
Ultrafiltration failure is a major complication of long-term peritoneal dialysis, resulting in dialysis failure. Peritoneal fibrosis induced by continuous exposure to high glucose dialysate is the major contributor of ultrafiltration failure, for which there is no effective treatment. Overactivation of several signaling pathways, including transforming
Longkai, Li, Nan, Shen, Nan, Wang, Weidong, Wang, Qingzhu, Tang, Xiangning, Du, Juan Jesus, Carrero, Keping, Wang, Yiyao, Deng, Zhitong, Li, Hongli, Lin, Taihua, Wu   +11 more
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