Core Genome Multilocus Sequence Typing and Antibiotic Susceptibility Prediction from Whole-Genome Sequence Data of Multidrug-Resistant Pseudomonas aeruginosa Isolates [PDF]
Microbiology Spectrum, 2022 Over the past decade, whole-genome sequencing (WGS) has overtaken traditional bacterial typing methods for studies of genetic relatedness. Further, WGS data generated during epidemiologic studies can be used in other clinically relevant bioinformatic ...
Scott A. Cunningham +5 more
doaj +5 more sources
Population structure analysis and laboratory monitoring of Shigella by core-genome multilocus sequence typing [PDF]
Nature Communications, 2022 Lab-based surveillance of Shigella has traditionally been based on serotyping but increasing availability of whole genome sequencing could enable higher resolution typing.
Iman Yassine +12 more
doaj +3 more sources
Delineating Mycobacterium abscessus population structure and transmission employing high-resolution core genome multilocus sequence typing [PDF]
Nature Communications, 2022 Mycobacterium abscessus is an emerging infection of increasing public health concern due to outbreaks and intrinsic multidrug-resistance. Here, the authors develop and evaluate a core-genome multilocus sequence typing scheme for this pathogen to ...
Margo Diricks +5 more
doaj +3 more sources
Establishment of a Publicly Available Core Genome Multilocus Sequence Typing Scheme for Clostridium perfringens [PDF]
Microbiology Spectrum, 2021 Clostridium perfringens is a spore-forming anaerobic pathogen responsible for a variety of histotoxic and intestinal infections in humans and animals.
Mostafa Y. Abdel-Glil +7 more
doaj +3 more sources
Epidemiological Investigation of Hospital Transmission of Corynebacterium striatum Infection by Core Genome Multilocus Sequence Typing Approach. [PDF]
Microbiology Spectrum, 2023 Recently, WGS of many human and animal pathogens has been successfully used to investigate microbial outbreaks. The cgMLST schema are powerful genotyping tools that can be used to investigate potential epidemics and provide classification of the strains ...
Yutong Kang, Jiang Yao, Xueli Ma
exaly +3 more sources
Development and Validation of a Burkholderia pseudomallei Core Genome Multilocus Sequence Typing Scheme To Facilitate Molecular Surveillance. [PDF]
Journal of Clinical Microbiology, 2021 Burkholderia pseudomallei causes the severe disease melioidosis. Whole-genome sequencing (WGS)-based typing methods currently offer the highest resolution for molecular investigations of this genetically diverse pathogen.
Sabine Lichtenegger +2 more
exaly +3 more sources
A Vibrio cholerae Core Genome Multilocus Sequence Typing Scheme To Facilitate the Epidemiological Study of Cholera. [PDF]
Journal of Bacteriology, 2020 Toxigenic Vibrio cholerae isolates of the O1 and O139 serogroups are the causative agents of cholera, an acute diarrheal disease that plagued the world for centuries, if not millennia.
Cheryl Tarr +2 more
exaly +3 more sources
Genus-wide Leptospira core genome multilocus sequence typing for strain taxonomy and global surveillance. [PDF]
PLoS Neglected Tropical Diseases, 2019 Leptospira is a highly heterogeneous bacterial genus that can be divided into three evolutionary lineages and >300 serovars. The causative agents of leptospirosis are responsible of an emerging zoonotic disease worldwide.
Julien Guglielmini +5 more
doaj +3 more sources
A Core Genome Multilocus Sequence Typing Scheme for Enterococcus faecalis. [PDF]
Journal of Clinical Microbiology, 2019 Among enterococci, Enterococcus faecalis occurs ubiquitously, with the highest incidence of human and animal infections. The high genetic plasticity of E. faecalis complicates both molecular investigations and phylogenetic analyses.
Jennifer K Bender +2 more
exaly +3 more sources
Development of the Pneumococcal Genome Library, a core genome multilocus sequence typing scheme, and a taxonomic life identification number barcoding system to investigate and define pneumococcal population structure. [PDF]
Microb Genom, 2023 Investigating the genomic epidemiology of major bacterial pathogens is integral to understanding transmission, evolution, colonisation, disease, antimicrobial resistance, and vaccine impact.
Jansen van Rensburg MJ +8 more
europepmc +2 more sources