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Study on the Effects and Mechanism of Corilagin on A2780 Cell Apoptosis [PDF]

open access: yesCurrent Issues in Molecular Biology
Previous studies have demonstrated corilagin’s inhibitory effects on the growth of various cancer cells. Given the limited research on corilagin’s impact on ovarian cancer, a particularly deadly gynecological malignancy, this study aimed to investigate ...
Ziyang Xu   +9 more
doaj   +4 more sources

Natural Polyphenol Corilagin Enhances Osteogenesis and Chondrogenesis Differentiation of Mesenchymal Stem Cells: Implications for Bone and Cartilage Regeneration [PDF]

open access: yesMolecules
Corilagin is a hydrolyzable ellagitannin and naturally occurring polyphenolic compound widely distributed in medicinal plants. It is also present in longan (Dimocarpus longan), known as lumyai in Thailand, a subtropical fruit extensively cultivated ...
Thitianan Kulsirirat   +3 more
doaj   +2 more sources

A Validated Isocratic HPLC–UV Method for the Simultaneous Quantification of Corilagin and Geraniin in Geranium wilfordii Maxim. Extract [PDF]

open access: yesMolecules
Geranium wilfordii Maxim. is a traditional medicinal plant rich in ellagitannins such as corilagin (CG) and geraniin (GR), which possess antioxidant and anti-inflammatory properties.
Jung-Min Kim   +4 more
doaj   +2 more sources

Unlocking the Therapeutic Potential of Ellagitannins: A Comprehensive Review of Key Representatives [PDF]

open access: yesMolecules
The present review offers a comprehensive synthesis of the structural diversity, natural occurrence, and therapeutic promise of key ellagitannins (punicalagin, sanguiin H-6, corilagin, geraniin, oenothein B, chebulagic, and chebulinic acids) within the ...
Rositsa Mihaylova   +3 more
doaj   +2 more sources

Comprehensive Analysis of Metabolic Changes in Mice Exposed to Corilagin Based on GC-MS Analysis [PDF]

open access: yesDrug Design, Development and Therapy
Biao Xu,1,* Changshui Wang,2,* Xiaodong Zhu,2 Li Zhu,3 Guangkui Han,2 Changmeng Cui2 1Clinical Medical School, Jining Medical University, Jining, 272067, People’s Republic of China; 2Department of Neurosurgery, Affiliated Hospital of Jining ...
Xu B, Wang C, Zhu X, Zhu L, Han G, Cui C
doaj   +2 more sources

Corilagin Inhibits Neutrophil Extracellular Trap Formation and Protects against Hydrochloric Acid/Lipopolysaccharide-Induced Acute Lung Injury in Mice by Suppressing the STAT3 and NOX2 Signaling Pathways [PDF]

open access: yesAntioxidants
Acute lung injury (ALI) and its severe manifestation, acute respiratory distress syndrome (ARDS), are characterized by uncontrolled inflammatory responses, neutrophil activation and infiltration, damage to the alveolar capillary membrane, and diffuse ...
Fu-Chao Liu   +4 more
doaj   +2 more sources

Molecular Dynamics Simulation of Bioactive Compounds Against Six Protein Target of Sars-Cov-2 As Covid-19 Antivirus Candidates [PDF]

open access: yesJurnal Kimia Valensi, 2021
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the virus that causes Coronavirus 2019 (COVID-19). To date, there has been no proven effective drug for the treatment or prevention of COVID-19.
Fikry Awaluddin   +2 more
doaj   +3 more sources

Corilagin alleviates atherosclerosis by inhibiting NLRP3 inflammasome activation via the Olfr2 signaling pathway in vitro and in vivo [PDF]

open access: yesFrontiers in Immunology
IntroductionAtherosclerosis, a leading cause of global cardiovascular mortality, is characterized by chronic inflammation. Central to this process is the NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome, which significantly influences ...
Jinqian Mao   +12 more
doaj   +2 more sources

In Vitro Inhibitory Activity of Corilagin and Punicalagin Against Toxoplasma gondii and Their Mechanism(s) of Action [PDF]

open access: yesAntibiotics
Background/Objectives: Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii. The parasite infection in humans continues to rise due to an increasing seroprevalence rate in domestic and wild warm-blooded animals that serve as a major reservoir ...
Nicole T. Green-Ross   +5 more
doaj   +2 more sources

High-Resolution LC-MS Simultaneous Quantification of Forty-Six Compounds from Jatropha podagrica Fruit Recommends Four Top Antioxidant Contributors as Q-Markers [PDF]

open access: yesMolecules
There has been no chemical analysis of the fruit of medicinal plant Jatropha podagrica until now. The current study aimed to qualitatively and quantitatively analyze the J.
Rongxin Cai   +7 more
doaj   +2 more sources

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