Results 41 to 50 of about 959,050 (193)

Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells

Redox Biology, 2020
Corneal transparency is maintained by a monolayer of corneal endothelial cells. Defects in corneal endothelial cells (CEnCs) can be rectified surgically through transplantation.
Matthew Lovatt, Khadijah Adnan, Viridiana Kocaba, Martin Dirisamer, Gary S.L. Peh, Jodhbir S. Mehta   +5 more
doaj   +1 more source

Inhibition of TGF-β signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine. [PDF]

PLoS ONE, 2013
Corneal endothelial dysfunctions occurring in patients with Fuchs' endothelial corneal dystrophy, pseudoexfoliation syndrome, corneal endotheliitis, and surgically induced corneal endothelial damage cause blindness due to the loss of endothelial function
Naoki Okumura, EunDuck P Kay, Makiko Nakahara, Junji Hamuro, Shigeru Kinoshita, Noriko Koizumi   +5 more
doaj   +1 more source

Descemet Stripping Endothelial Keratoplasty for Congenital Aniridia: An Interesting and Challenging Story

Türk Oftalmoloji Dergisi, 2022
Congenital aniridia is a rare condition affecting a wide range of ocular structures, from the ocular surface to the retina. We present the case of a 59-year-old woman with PAX6- and WT1-negative congenital aniridia who developed aniridia-associated ...
Ioannis Athanasiadis, Michael Tsatsos, Nikolaos Ziakas   +2 more
doaj   +1 more source

Evaluation of interface quality in organ-cultured lamellar corneal transplants [PDF]

, 2012
Background: With increasing numbers of lamellar keratoplasties, eye banks are challenged to deliver precut lamellar donor tissue. In Europe, the most common technique of corneal storage is organ culture which requires a deswelling process before surgical
Kohnen, Thomas, Wolf, Armin, Kook, Daniel, Grüterich, Martin, Jagow, Burkhard von, Kampik, Anselm, Lackerbauer, Carlo A., Messmer, Elisabeth M.   +7 more
core   +1 more source

Treatment of periodontitis and endothelial function [PDF]

, 2007
Background: Systemic inflammation may impair vascular function, and epidemiologic data suggest a possible link between periodontitis and cardiovascular disease.
Deanfield, John, Nibali, Luigi, Suvan, Jean, Vallance, Patrick, Storry, Clare, Nibali, L., Donald, Ann, D'Aiuto, F., Storry, C., Parkar, Mohamed, Vallance, P., Hingorani, A.D., Tonetti, Maurizio S., Parkar, M., Deanfield, J., Hingorani, Aroon D., Suvan, J., Donald, A., D'Aiuto, Francesco, Tonetti, M.S.   +19 more
core   +1 more source

The Evolving Therapeutics of Endothelial Disease

, 2023
Endothelial dysfunction is one of the leading indications for corneal transplantation. Globally, there is a shortage of donor corneas, which is partly because of the lack of eye banking resources in emerging countries.
Koo, Ellen H., Huertas-Bello, Marcela, Sabater, Alfonso L.   +2 more
core   +1 more source

Review: corneal endothelial cell derivation methods from ES/iPS cells

Inflammation and Regeneration, 2019
Globally, approximately 12.7 million people are awaiting a transplantation, while only 185,000 cases of corneal transplantation are performed in a year. Corneal endothelial dysfunction (bullous keratopathy) due to Fuchs’ corneal endothelial dystrophy, or
Shin Hatou, Shigeto Shimmura
doaj   +1 more source

Loss of Corneal Endothelial Cells during Glaucoma Surgery

Oftalʹmologiâ, 2020
As known, there are changes in the biomechanical properties of the fibrous tunic in glaucoma. This is also due to the imbalance between the formation and loss of collagen fibers.
I. V. Shaposhnikova, I. R. Gazizova, A. V. Kuroyedov, A. V. Seleznev, D. N. Lovpache   +4 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Research progress of corneal endothelial cell regeneration and replacement

Eye & ENT Research
Corneal endothelial cells (CECs) are crucial for the maintenance of corneal transparency and normal visual function. Corneal endothelial dysfunction can lead to corneal edema, opacity, and even blindness.
Zongyi Li, Haoyun Duan, Qingjun Zhou
doaj   +1 more source