Resuscitation of newborn piglets. short-term influence of FiO2 on matrix metalloproteinases, caspase-3 and BDNF. [PDF]
PLoS ONE, 2010 BACKGROUND: Perinatal hypoxia-ischemia is a major cause of mortality and cerebral morbidity, and using oxygen during newborn resuscitation may further harm the brain.
Rønnaug Solberg +7 more
doaj +1 more source
Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy. [PDF]
, 2015 BackgroundMultiple system atrophy (MSA) is a neurodegenerative disease characterized by parkinsonism, ataxia and dysautonomia. Histopathologically, the hallmark of MSA is the abnormal accumulation of alpha-synuclein (α-syn) within oligodendroglial cells,
Adame, Anthony +12 more
core +2 more sources
Compulsive Social Behavior Emerges after Selective Ablation of Striatal Cholinergic Interneurons [PDF]
, 2017 The mechanisms underlying social dysfunction in neuropsychiatric conditions like obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) remain uncertain. Dysfunctions in basal ganglia, including reduced number of striatal cholinergic interneurons
Beccaria, Juan Pablo +4 more
core +1 more source
Connectivity Alterations in Vascular Parkinsonism: A Structural Covariance Study
Applied Sciences, 2022 This study aimed to investigate the structural covariance between the striatum and large-scale brain regions in patients with vascular parkinsonism (VP) compared to Parkinson’s disease (PD) and control subjects, and then explore the relationship between ...
Fabiana Novellino +8 more
doaj +1 more source
Susceptibility Weighted Imaging as a Useful Imaging Adjunct in Hemichorea Hyperglycaemia
Case Reports in Radiology, 2013 Hyperglycaemia with hemichorea (HGHC) is an unusual clinical entity that can be associated with corpus striatum hyperintensity on T1-weighted (T1W) magnetic resonance imaging (MRI) sequences.
Ferry Dharsono +3 more
doaj +1 more source
Frontiers in Neurology, 2018 Although intracerebral hemorrhage (ICH) is a devastating disease worldwide, the pathologic changes in ultrastructure during the acute and chronic phases of ICH are poorly described.
Qian Li +13 more
doaj +1 more source
Involvement of the cortico-basal ganglia-thalamocortical loop in developmental stuttering [PDF]
, 2019 Stuttering is a complex neurodevelopmental disorder that has to date eluded a clear explication of its pathophysiological bases. In this review, we utilize the Directions Into Velocities of Articulators (DIVA) neurocomputational modeling framework to ...
Chang, Soo-Eun, Guenther, Frank H.
core +1 more source
Delayed-onset parkinsonism is common after isolated striatal infarcts
Frontiers in NeurologyBackgroundWhile case studies have suggested that only a minority of patients with putaminal lesions develop parkinsonism, existing data are limited by involvement of adjacent brain regions, brief follow-up period, and lack of systematic imaging.
Hedda Holm +11 more
doaj +1 more source
Golgi Protein ACBD3 Mediates Neurotoxicity Associated with Huntington’s Disease
Cell Reports, 2013 Huntington’s disease (HD) is an autosomal-dominant neurodegenerative disease caused by the expansion of polyglutamine repeats in the gene for huntingtin (Htt).
Juan I. Sbodio +3 more
doaj +1 more source
Enhanced pre-frontal functional-structural networks to support postural control deficits after traumatic brain injury in a pediatric population [PDF]
, 2017 Traumatic brain injury (TBI) affects the structural connectivity, triggering the re-organization of structural-functional circuits in a manner that remains poorly understood.
Bonifazi, Paolo +7 more
core +3 more sources