Results 131 to 140 of about 575,401 (181)

Cortical Spreading Depolarization, Blood Flow, and Cognitive Outcomes in a Closed Head Injury Mouse Model of Traumatic Brain Injury. [PDF]

Neurocrit Care, 2022
Mosley N, Chung JY, Jin G, Franceschini MA, Whalen MJ, Chung DY.   +5 more
europepmc   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, Volume 100, Issue 3, Page 458-476, September 2026.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

Chronic Paraquat Neurotoxicity and Dopaminergic Degeneration: A Mechanistic Review

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Occurrence of Parkinson's disease (PD) based on several neurotoxins. Advanced and comprehensive mechanisms based on Paraquat‐induced PD. Mechanism of oxidative stress, ROS and RNS formation, and death of dopaminergic neurons. The modulation of genes and proteins by paraquat leads to Parkinsonism.
Saima Riaz, Shaukat Ali, Muhammad Summer, Amina Iqbal, Rimsha Ashraf, Ramzana Bibi   +5 more
wiley   +1 more source

Parvalbumin interneurons in Alzheimer's disease: Physiological insights and pathophysiological mechanisms

Journal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
Physiological and Pathological Alterations in PV+ Neurons: Under physiological conditions, PV+ interneurons exhibit fast‐spiking properties and generate gamma oscillations at the cost of high energy consumption. In AD, PV+ neurons display abnormalities in ion channels, dendrites, neurotransmission, energy metabolism, and neural oscillations, ultimately
Mengyan Wu, Xingdong Zeng, Yongle Cai, Haonan Chen, Qianying Li, Hao Yang   +5 more
wiley   +1 more source

Assessing Ageing Condition of Mineral Oil-Paper Insulation by Polarization/Depolarization Current

, 2011
Accurately assessing the ageing status of oil-paper insulation in transformer is essential and important. Polarization and Depolarization Current (PDC) technique is effective in assessing the condition of oil-paper insulation system.
Liao, R, Hao, J, Yang, L, Ma, Z, Chen, G
core   +1 more source

Ganoderic Acid A Ameliorates Pentylenetetrazol‐Induced Epilepsy in Mice via Activating KCNQ2

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
GA‐A binds and activates KCNQ2, thereby reducing epileptic‐like EEG discharges, the loss and apoptosis of hippocampal neurons, and improving anxiety and depression‐like behavioral changes. In addition, GA‐A inhibits neuroinflammation and alleviates oxidative stress independent of activating KCNQ2.
Yang Yao, Zhujun Liu, Xujiao Wang, Cunhao Bian, Rui Wang, Yukun Zhang   +5 more
wiley   +1 more source

Mechanisms underlying CSD initiation implicated by genetic mouse models of migraine

The Journal of Headache and Pain
A key unanswered question in migraine neurobiology concerns the mechanisms that make the brain of migraineurs susceptible to cortical spreading depression (CSD, a spreading depolarization that underlies migraine aura and may trigger the migraine pain ...
Daniela Pietrobon, K.C. Brennan
doaj   +1 more source

Preparation of Acute Mouse Hippocampal Brain Sections for Transport to a Distant Electrophysiology Laboratory

Current Protocols, Volume 6, Issue 9, September 2026.
Abstract This article describes a standardized method for preparing and transporting acute mouse hippocampal brain slices suitable for high‐quality single‐cell, CA1, pyramidal cells electrophysiological recordings between laboratories in departments or institutions located at distances up to 3 hr apart.
Sofia Ioanna Nouka, Loukia Katsouri, Jonathan Rudge, John O'Keefe, Francesco Tamagnini   +4 more
wiley   +1 more source

Commentary: Enhanced Hemodynamic and Clinical Response to αCGRP in Migraine Patients—A TCD Study

Frontiers in Neurology, 2021
Claudia Altamura, Fabrizio Vernieri
doaj   +1 more source

Deletion of Astrocytic TNFR1 Attenuates Hyperexcitability and Initiation of Epileptogenesis

Glia, Volume 74, Issue 9, September 2026.
Inducible, astrocyte‐specific deletion of TNFR1 reduces basal EEG spectral power. Loss of astrocytic TNFR1 attenuates acute seizure activity in two distinct experimental models of epilepsy. Deletion of TNFR1 in astrocytes limits epilepsy development and hippocampal pathology in a mouse model of temporal lobe epilepsy with hippocampal sclerosis ...
Lukas Henning, Ioannis Zalachoras, Giovanni Carriero, Gerald Seifert, Peter Bedner, Christian Steinhäuser, Andrea Volterra   +6 more
wiley   +1 more source