Results 161 to 170 of about 1,085 (173)

Cosmc Is Essential for O-Glycosylation of Platelet Glycoproteins and Platelet Function

Blood, 2010
Abstract Abstract 383 Platelets express a large number of glycoproteins involved in adhesion and signaling events, but the specific roles of the Asn-linked (N-glycans) and Ser/Thr-linked (O-glycans) pathways are not well understood.
Yingchun Wang, Shawn Jobe, Xiaokun Ding, David R. Archer, Rongjuan Mi, Tongzhong Ju, Richard Cummings   +6 more
openaire   +1 more source

Immunocytochemical analysis for intracellular dynamics of C1GalT associated with molecular chaperone, Cosmc

Biochemical and Biophysical Research Communications, 2008
The core 1 structure Galbeta1-3GalNAcalpha1-Ser/Thr (T antigen), the major constituent of O-glycan core structure, is synthesized by cooperation of core 1 synthase (C1GalT) and its specific molecular chaperone, Cosmc. The chaperone function of Cosmc has been well investigated biochemically.
Yoshiki, Narimatsu, Yuzuru, Ikehara, Hiroko, Iwasaki, Chizu, Nonomura, Takashi, Sato, Hayao, Nakanishi, Hisashi, Narimatsu   +6 more
openaire   +2 more sources

Human Tumor Antigens Tn and Sialyl Tn Arise from Mutations in Cosmc

Cancer Research, 2008
Abstract Neoplastic lesions typically express specific carbohydrate antigens on glycolipids, mucins, and other glycoproteins. Such antigens are often under epigenetic control and are subject to reversion and loss upon therapeutic selective pressure.
Tongzhong, Ju, Grainger S, Lanneau, Tripti, Gautam, Yingchun, Wang, Baoyun, Xia, Sean R, Stowell, Margaret T, Willard, Wenyi, Wang, Jonathan Y, Xia, Rosemary E, Zuna, Zoltan, Laszik, Doris M, Benbrook, Marie H, Hanigan, Richard D, Cummings   +13 more
openaire   +2 more sources

[Cosmc: the ''chaperone'' toward the understanding of IgA Nephropathy?].

Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia, 2009
NA
openaire   +3 more sources

[Association of Cosmc gene mutation with susceptibility to Henoch-Schönlein purpura in children].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2016
To investigate the presence of Cosmc gene mutation in children with Henoch-Schönlein purpura (HSP) and the association between Cosmc gene mutation and the susceptibility to HSP.Eighty-four children who were diagnosed with HSP between March 2014 and December 2015 were selected as the HSP group. Fifty-eight healthy volunteers matched for age and sex were
Qiu-Ling, Xie, Xi, Mo, Shao-Ling, Liu, Ming-Ang, Zhu, Yue, Tao, Xiao-Qin, Zhang, Jian, Wang, Yan-Liang, Jin   +7 more
openaire   +1 more source

Cosmc overexpression enhances malignancies in human colon cancer

Journal of Cellular and Molecular Medicine, 2020
Tan Du, Tao Wen
exaly  

SLC35A2 deficiency reduces protein levels of core 1 β-1,3-galactosyltransferase 1 (C1GalT1) and its chaperone Cosmc and affects their subcellular localization

Biochimica Et Biophysica Acta - Molecular Cell Research, 2023
Mariusz Olczak, Dorota Maszczak-Seneczko, Wojciech Wiertelak   +2 more
exaly  

Absence of COSMC gene mutations in breast and colorectal carcinomas

APMIS, 2008
Nam Jin Yoo, Min Sung Kim, Sug Hyung Lee
openaire   +1 more source

[Progression in the mechanism of the Cosmc in IgA nephropathy].

Zhonghua er ke za zhi = Chinese journal of pediatrics, 2014
Nan, Zhou, Ying, Shen
openaire   +1 more source

Mycophenolic acid reverses IgA1 aberrant glycosylation through up-regulating Cosmc expression in IgA nephropathy

International Urology and Nephrology, 2012
Ping Fu, Wei Qin
exaly