Results 21 to 30 of about 1,431 (214)

Covalent Modifications of the Ebola Virus Glycoprotein [PDF]

Journal of Virology, 2002
ABSTRACT The role of covalent modifications of the Ebola virus glycoprotein (GP) and the significance of the sequence identity between filovirus and avian retrovirus GPs were investigated through biochemical and functional analyses of mutant GPs.
Scott A, Jeffers, David Avram, Sanders, Anthony, Sanchez   +2 more
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Weighing the Proteasome for Covalent Modifications

Chemistry & Biology, 2015
Posttranslational modifications (PTMs) control protein function, but established peptide-based proteomic methods often fail to provide a comprehensive view of PTMs. In this issue of Chemistry & Biology, Gersch et al. describe an efficient combination of chromatographic separation and top-down mass spectrometry that together with an intuitive ...
Birner-Gruenberger, Ruth, Breinbauer, Rolf   +1 more
openaire   +2 more sources

Research Progress on Graphene/Polymer Composites with Non-covalent Surface Modification

Cailiao gongcheng, 2018
Graphene possesses excellent mechanical, electrical and thermal properties, which has been wildly used in modification of polymer composites. However, graphene has poor compatibility with polymers due to its surface inactive properties.
WANG Hao, ZHANG Hui, ZHANG Ji-hua, ZHAO Yun-feng   +3 more
doaj   +1 more source

Chemical strategies for the covalent modification of filamentous phage [PDF]

Frontiers in Microbiology, 2014
Historically filamentous bacteriophage have been known to be the workhorse of phage display due to their ability to link genotype to phenotype. More recently, the filamentous phage scaffold has proven to be powerful outside the realm of phage display technology in fields such as molecular imaging, cancer research and materials, and vaccine development.
Matthew B Francis, Matthew B Francis, Jenna Marie Lee Bernard, Jenna Marie Lee Bernard   +3 more
openaire   +5 more sources

Covalent post-assembly modification in metallosupramolecular chemistry [PDF]

Chemical Society Reviews, 2018
This review examines the growing variety of covalent reactions used to achieve the post-assembly modification of self-assembled metallosupramolecular complexes.
Derrick A. Roberts, Ben S. Pilgrim, Jonathan R. Nitschke   +2 more
openaire   +3 more sources

Dimethyl Fumarate Induces Metabolic Crisie to Suppress Pancreatic Carcinoma

Frontiers in Pharmacology, 2021
Dimethyl fumarate (DMF) is an approved drug used in the treatment of multiple sclerosis (MS) and psoriasis therapy. Multiple studies have demonstrated other pharmacological activities of DMF such as an anti-cancer agent. In particular, studies have shown
Kaiyuan Chen, Shanshan Wu, Shanshan Wu, Sisi Ye, Sisi Ye, Huimin Huang, Yi Zhou, Hongfei Zhou, Shijia Wu, Yefan Mao, Fugen Shangguan, Linhua Lan, Bicheng Chen   +12 more
doaj   +1 more source

Comparison of stability and thermophysical properties of CNT–GNP hybrid nanofluids using different surface modification techniques

Cogent Engineering
This study examines how non-covalent and covalent surface modification methods affect the stability and thermo-physical characteristics of carbon nanotubes (CNTs) and graphene platelets (GNP) when distributed in solar thermal fluids.
Bhanuteja Sanduru, Srinivas Vadapalli, Kosaraju Satyanarayana, Darya Viktorovna Nemova, Ankita Joshi   +4 more
doaj   +1 more source

Chemical modification of the lectin of the marine coral Gerardia savaglia by marine quinone avarone [PDF]

Journal of the Serbian Chemical Society, 2007
The quinone avarone, isolated from the marine sponge Dysidea avara, possesses the ability to chemically modify proteins. In this work, modification of lectin isolated from the coral Gerardia savaglia by avarone was examined.
IVANA PAJIC, ZORAN VUJCIC, MIROSLAVA VUJCIC, IRENA NOVAKOVIC, DUSAN SLADIC, MIROSLAV J. GASIC   +5 more
doaj   +3 more sources

Quantitative Irreversible Tethering (qIT) for Target-directed Covalent Fragment Screening

Bio-Protocol, 2020
Small molecules that react to form covalent bonds with proteins are widely used as biological tools and therapeutic agents. Screening cysteine-reactive fragments against a protein target is an efficient way to identify chemical starting points for ...
Gregory Craven, David Mann, Alan Armstrong   +2 more
doaj   +1 more source

Implications of Widespread Covalent Modification of mRNA [PDF]

Circulation Research, 2012
Whole transcriptome analysis reveals that one third of human and mouse genes express mRNAs containing methylated adenosines. Fat mass and obesity-associated ( FTO ) gene, a risk gene for obesity and metabolic abnormalities, demethylates the modified residues, suggesting a link between RNA methylation and disease.
openaire   +2 more sources