Results 31 to 40 of about 2,379,457 (382)

Novel nicotinoid structures for covalent modification of wood: an environmentally friendly way for its protection against insects. [PDF]

RSC Adv, 2020
Söftje M, Acker S, Plarre R, Namyslo JC, Kaufmann DE.   +4 more
europepmc   +3 more sources

Fundamental aspects of the non-covalent modification of cellulose via polymer adsorption.

Advances in Colloid and Interface Science, 2021
The increasing need for new material applications based on cellulose demands increased functional diversity and thus new functionalisation/modification approaches.
Vishnu Arumughan, Tiina Nypelö, Merima Hasani, A. Larsson   +3 more
semanticscholar   +1 more source

A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II

Biomolecules, 2020
Fragment screening is a powerful tool to identify and characterize binding pockets in proteins. We herein present the results of a proof-of-concept screening campaign of a versatile 96-entry fragment library from our laboratory against the drug target ...
Steffen Glöckner, Andreas Heine, Gerhard Klebe   +2 more
doaj   +1 more source

A covalent BTK ternary complex compatible with targeted protein degradation

Nature Communications, 2023
Bridging covalent ligand discovery with chimeric degrader design has emerged as a mechanism to target proteins that lack enzymatic activity or are intractable.
James Schiemer, Andrew Maxwell, Reto Horst, Shenping Liu, Daniel P. Uccello, Kris Borzilleri, Nisha Rajamohan, Matthew F. Brown, Matthew F. Calabrese   +8 more
doaj   +1 more source

The high thermal conductive and flexible boron nitride/silicone rubber composites with segregated structure

Materials Research Express, 2021
Silicone rubber (SR) composites filled with silicone rubber particles (SRP) and functionalized h-BN platelets were successfully prepared, which have high thermal conductivities and flexibility.
Jiwan Ding, Ruobing Zheng, Yajie Zhang, Xian Zhang, Gang Liu, Kang Zheng   +5 more
doaj   +1 more source

Comparative study of collagen and gelatin coatings on titanium surfaces [PDF]

, 2010
The vast majority of studies in the bone tissue engineering field are focused on the surface modification of titanium scaffolds to obtain integration of the scaffold in the surrounding bone tissue. Our approach consisted in benefiting from the advantages
Cacchioli, Cai, de Jonge, de Jonge, Douglas, Dubruel, Dupont-Gillain, Endo, Fischer, Friess, Geissler, Habibovic, Harle, Harnett, Heydari, Kozlov, Kuangl, Lee, Liu, MacDonald, Meena, Morra, Muller, Nanci, Porté-Durrieu, Puleo, Puleo, Rammelt, Roehlecke, Rohanizadeh, Ulubayram, Van den Bulcke, Van Vlierberghe, Van Vlierberghe, Weng, Wissink, Xiao, Yan, Yang, Yang   +39 more
core   +2 more sources

5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme [PDF]

, 2015
5-hydroxymethylcytosine is a new epigenetic modification deriving from the oxidation of 5-methylcytosine by the TET hydroxylase enzymes. DNA hydroxymethylation drives DNA demethylation events and is involved in the control of gene expression ...
CAIAFA, Paola, CICCARONE, FABIO, VALENTINI, ELISABETTA, ZAMPIERI, Michele   +3 more
core   +2 more sources

Covalent lipid modifications of proteins [PDF]

Current Biology, 2013
SummaryAttachment of lipophilic groups is a widespread modification that occurs on nearly 1,000 proteins of diverse structure and function. At least five different types of lipids can be covalently attached to proteins: fatty acids, isoprenoids, sterols, phospholipids, and glycosylphosphatidyl inositol (GPI) anchors.
openaire   +2 more sources

Technologies for Direct Detection of Covalent Protein–Drug Adducts

Pharmaceuticals, 2023
In the past two decades, drug candidates with a covalent binding mode have gained the interest of medicinal chemists, as several covalent anticancer drugs have successfully reached the clinic. As a covalent binding mode changes the relevant parameters to
Elma Mons, Robbert Q. Kim, Monique P. C. Mulder   +2 more
doaj   +1 more source

A Review on Development of Ceramic-Graphene Based Nanohybrid Composite Systems in Biological Applications

Frontiers in Chemistry, 2021
Graphene-based nanocomposites constitute an interesting and promising material for various applications. Intensive progress in the development of this group of materials offers an opportunity to create new systems useful for drinking water ...
Michał Jakubczak, Agnieszka M. Jastrzębska   +1 more
doaj   +1 more source