Identification of the Optimal Pattern of the Injection and Dosage of DC Immunotherapy Using the Mathematical Models Based on Ordinary Differential Equations [PDF]
Iranian Journal of Immunology, 2022 Background: Mathematical modeling offers the possibility to select the optimal dose of a drug or vaccine. Considerable evidence show that many bacterial components can activate dendritic cells (DCs). Our previous report showed that multiple doses of DCs
Bahareh Zand +8 more
doaj +1 more source
Journal of Petroleum Exploration and Production Technology, 2023 Despite significant advancements in geomodelling technologies, accurately estimating hydraulic fracture half-length remains a challenging task. This paper introduces a detailed estimation approach using the Gaussian Pressure Transient (GPT) method, which
Dandi Alvayed +5 more
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Multi-neuronal refractory period adapts centrally generated behaviour to reward [PDF]
, 2012 Oscillating neuronal circuits, known as central pattern generators (CPGs), are responsible for generating rhythmic behaviours such as walking, breathing and chewing.
Anil K. Seth +7 more
core +7 more sources
Genome-wide CpG density and DNA methylation analysis method (MeDIP, RRBS, and WGBS) comparisons
Epigenetics, 2021 Genome-wide DNA methylation analysis is one of the most common epigenetic processes analysed for genome characterization and differential DNA methylation assessment.
Daniel Beck +2 more
semanticscholar +1 more source
Preservation of methylated CpG dinucleotides in human CpG islands [PDF]
Biology Direct, 2016 CpG dinucleotides are extensively underrepresented in mammalian genomes. It is widely accepted that genome-wide CpG depletion is predominantly caused by an elevated CpG > TpG mutation rate due to frequent cytosine methylation in the CpG context. Meanwhile the CpG content in genomic regions called CpG islands (CGIs) is noticeably higher.
Panchin, Alexander Y. +2 more
openaire +2 more sources
The emergence of the brain non-CpG methylation system in vertebrates
Nature Ecology & Evolution, 2021 Mammalian brains feature exceptionally high levels of non-CpG DNA methylation alongside the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role in cognitive function, which is mediated by the binding of MeCP2, the ...
Alex de Mendoza +17 more
semanticscholar +1 more source
Autonomous gait modulation in a cat hind leg simulation model based on the spinal nervous system
Nihon Kikai Gakkai ronbunshu, 2020 This study aims to design a nervous system model to drive the realistic muscle-driven legs for quadrupedal robot locomotion. In this paper, we evaluate the nervous system model.
Yasushi HABU +4 more
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Organic Matter Burial in Deep-Sea Fans: A Depositional Process-Based Perspective
Journal of Marine Science and Engineering, 2022 Organic matter burial in the deep-sea fan sediments is an important component of the long-term carbon cycle. Although there is increasing recognition of the importance of organic matter in deep-sea sediments, a major focus has been on mudstones, commonly
Arif Hussain, Khalid Al-Ramadan
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Policy for developing clinical practice guidelines of Japanese Society for Dialysis Therapy
Renal Replacement Therapy, 2017 Background The Scientific Academy Committee of Japanese Society for Dialysis Therapy (JSDT) has developed 14 clinical practice guidelines (CPGs) and their revised editions independently or in cooperation with other organizations and translated many of ...
Kosaku Nitta +20 more
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Use of Urology-Based Clinical Practice Guidelines in International Settings
Société Internationale d’Urologie Journal, 2021 ObjectiveClinical practice guidelines (CPGs) serve as frameworks to unify diagnostic criteria and guide clinical decision-making. There is a paucity of literature surrounding the uptake of CPGs in urology practice settings with varied ...
German Patino, Medina Ndoye, Hannah Thomas, Andrew Cohen, Nnenaya Mmonu, Carissa Chu, Benjamin Breyer
doaj +1 more source