Results 181 to 190 of about 152,781 (323)

An origin of bidirectional DNA replication is located within a CpG island at the 3' end of the chicken lysozyme gene [PDF]

, 1999
P.-v. Loc, Wolf H. Strätling
openalex   +1 more source

Direct Immunologic activities of CpG DNA and implications for gene therapy [PDF]

, 1999
Arthur Μ. Krieg
openalex   +1 more source

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

Chemistry &Biodiversity, EarlyView.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang, Huiling Liu, Bingdong Zhu, Wen Li, Xue Han, Jiaojiao Fu, Renjie Luo, Haiyan Wang, Jinxia Wang   +8 more
wiley   +1 more source

Significant Differences in the Frequency of Transcriptional Units, Types and Numbers of Repetitive Elements, GC Content, and the Number of CpG Islands Between a 1010-kb G-band Genomic Segment on Chromosome 9q31.3 and a 1200-kb R-band Genomic Segment on Chromosome 3p21.3 [PDF]

, 1999
Yataro Daigo, Minoru Isomura, Tadashi Nishiwaki, Kazufumi Suzuki, Osamu Maruyama, Kumiko Takeuchi, Yuka Yamane, Rie Hayashi, Maiko Minami, Yoshiaki Hojo, Ikuo Uchiyama, Toshihisa Takagi, Yusuke Nakamura   +12 more
openalex   +1 more source

Methylation of CpG loci in 5?-flanking region alters steady-state expression of adenomatous polyposis coli gene in colon cancer cell lines [PDF]

, 2000
Yoshio Sakamoto, Riko Kitazawa, Sakan Maeda, Sohei Kitazawa   +3 more
openalex   +1 more source

Rainbow™ Universal CPG: A Versatile Solid Support for Oligonucleotide Synthesis

, 1997
Paul S. Nelson, Sylvester Muthini, Mike Vierra, L. Acosta, Thomas H. Smith   +4 more
openalex   +1 more source

Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a [PDF]

, 2000
Bernard Ramsahoye, Detlev Biniszkiewicz, Frank Lyko, Victoria H. Clark, Adrian Bird, Rudolf Jaenisch   +5 more
openalex   +1 more source

A Robust Strategy for Introducing Amino‐Modifiers in Nucleic Acids: Enabling Novel Amino Tandem Oligonucleotide Synthesis in DNA and RNA

Chemistry – A European Journal, EarlyView.
We report a simple, efficient, and cost‐effective methodology for introducing amino‐modifiers into DNA and RNA using a commercially available solid support. By incorporating a base‐labile sulfonyl linker within the strand, we developed an amino‐containing tandem oligonucleotide synthesis (aTOS) methodology, which enables the introduction of multiple ...
Jagandeep S. Saraya, Nicholas G. Horton, Scott R. Sammons, Derek K. O′Flaherty   +3 more
wiley   +1 more source

New Pyridobenothiazolone Derivatives Display Nanomolar Pan‐Serotype Anti‐Dengue Virus Activity

ChemMedChem, EarlyView.
A ligand‐based strategy is employed, starting from hit compound 2, to develop the C‐2 modified pyridobenzothiazolone 19 as a pan‐serotype nanomolar DENV‐1‐4 inhibitor. Investigations of the mechanism reveal the peculiar ability to abolish the infectivity of virions in a second infection.
Tommaso Felicetti, Chin Piaw Gwee, Kitti Wing Ki Chan, Giacomo Pepe, Ciro Milite, Pietro Campiglia, Satoru Watanabe, Muhammad Danial Bin Mohd Mazlan, Stefano Sabatini, Serena Massari, Oriana Tabarrini, Gianluca Sbardella, Subhash G. Vasudevan, Giuseppe Manfroni   +13 more
wiley   +1 more source

Pig and quail CpG methylation datasets from short and long read sequencing technologies. [PDF]

Sci Data
Terzian P, Vandecasteele C, Lledo J, Serre RF, Sabban J, Kuchly C, Pitel F, Leroux S, Demars J, Iannuccelli N, Fève K, Bonnet M, Gaspin C, Milan D, Iampietro C, Klopp C, Donnadieu C.   +16 more
europepmc   +1 more source