Covalent Attachment of a Platinum(II) Complex inside DNA Duplexes
Oxidative addition is used for the site‐specific incorporation of an organometallic PtII complex as an artificial nucleobase into a DNA duplex. The platination stabilizes the duplex and confers it with phosphorescence. An organometallic phosphorescent PtII complex is introduced into DNA duplexes via oxidative addition to a tailor‐made artificial ...
Tim Schäfer +6 more
wiley +1 more source
The Peripheral Epigenome Predicts White Matter Volume Contingent on Developmental Stage: An ECHO Study. [PDF]
Hanson T +12 more
europepmc +1 more source
Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang +5 more
wiley +1 more source
Intra-articular Hyaluronic Acid for Knee Osteoarthritis: Stabilizing Utilization Trends Amid Conflicting Clinical Practice Guidelines. [PDF]
Lee CJ, Lee AH, Day W, Grauer JN.
europepmc +1 more source
Hepatitis B vaccination with HepB-CpG in people living with HIV: a narrative review
Kelvin McKoy +3 more
openalex +1 more source
Mechanisms of resistance to cancer immunotherapy from a host–tumor interaction perspective. The central tumor cell is protected by multiple resistance mechanisms, including genetic mutations, epigenetic modifications, and metabolic alterations. The immunosuppressive tumor microenvironment features myeloid‐derived suppressor cells (MDSCs), regulatory T ...
Mohammed Elmujtba Adam Essa +2 more
wiley +1 more source
Stratifying high-risk prediabetes clusters using blood-based epigenetic markers. [PDF]
Singh A +15 more
europepmc +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source
Pre-activation timing determines influenza severity and viral pathogenicity via STING Inhibition. [PDF]
Zhu T +9 more
europepmc +1 more source

