Results 11 to 20 of about 370,062 (234)
A vaccine formulated with the major outer membrane protein can protect C3H/HeN, a highly susceptible strain of mice, from a Chlamydia muridarum genital challenge. [PDF]
, 2015 C3H/HeN female mice were vaccinated with native Chlamydia muridarum major outer membrane protein (MOMP), using Montanide+CpG or Alum+CpG as adjuvants. Negative control groups were immunized with ovalbumin (OVA) and the same adjuvants. As positive control,
de la Maza, Luis M +2 more
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CpG and Interleukin-15 Synergize to Enhance IFN-γ Production by Activated CD8+ T Cells [PDF]
, 2012 Interleukin-15 (IL-15) regulates the development and maintenance of memory CD8+ T cells. Paradoxically, we previously reported that IL-15 could enhance CD8+ T-cell responses to IL-12, a proinflammatory cytokine required for optimal priming of effector ...
Cobb, Dustin +2 more
core +5 more sources
Scientific Reports, 2020 The COVID-19 pandemic is a worldwide health emergency which calls for an unprecedented race for vaccines and treatment. In developing a COVID-19 vaccine, we applied technology previously used for MERS-CoV to produce a prefusion-stabilized SARS-CoV-2 ...
T. Kuo +13 more
semanticscholar +1 more source
Nutrition & Santé, 2023 Introduction. The natural plant resources are products with high added value, used in various fields for the manufacture of a wide variety of products. Objective.
Razika LAOUFI +5 more
doaj +1 more source
Extreme Genomic CpG Deficiency in SARS-CoV-2 and Evasion of Host Antiviral Defense
Molecular biology and evolution, 2020 Wild mammalian species, including bats, constitute the natural reservoir of betacoronavirus (including SARS, MERS, and the deadly SARS-CoV-2). Different hosts or host tissues provide different cellular environments, especially different antiviral and RNA
X. Xia
semanticscholar +1 more source
THE PROBLEM OF GENDER VOTING IN THE WEIMAR REPUBLIC
RUDN Journal of World History, 2018 The article is devoted to the problem of gender vote in the Weimar republic: what were political preferences of the German women of that period, who only had acquired the right to vote under the new constitution.
Eduard E Shults
doaj +1 more source
Metalloproteinases and their Inhibitors under the Course of Immunostimulation by CPG-ODN and Specific Antigen Inhalation in Equine Asthma [PDF]
, 2019 Objectives. Inhalation of immunostimulatory bacterial DNA segments (cytosine-phosphate-guanosine-oligodeoxynucleotides, CpG-ODN) normalizes clinical and cytologic parameters in severe equine asthma.
Barton, Ann Kristin +5 more
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CpG islands and the regulation of transcription.
Genes & Development, 2011 Vertebrate CpG islands (CGIs) are short interspersed DNA sequences that deviate significantly from the average genomic pattern by being GC-rich, CpG-rich, and predominantly nonmethylated.
A. Deaton, A. Bird
semanticscholar +1 more source
The Basis of Anticancer Immunity Mechanism Induced by In Situ Vaccination [PDF]
Журнал Сибирского федерального университета: Серия Биология, 2020 The present review is an attempt to characterize the principles of both onset and development of the systemic antitumor immune response triggered by in situ vaccination, which is a new trend in anticancer immunotherapy.
Anastasia S. Proskurina +7 more
doaj +1 more source
, 2005 Toll-like receptor (TLR)-9 recognizes CpG motifs in microbial DNA. TLR9 signalling stimulates innate antimicrobial immunity and modulates adaptive immune responses including autoimmunity against chromatin, e.g., in systemic lupus erythematosus (SLE ...
Anders HJ, H-J Anders, Stacey KJ
core +1 more source