Results 31 to 40 of about 152,781 (323)

CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function [PDF]

Genes, 2017
DNA methylation is a major epigenetic mark with important roles in genetic regulation. Methylated cytosines are found primarily at CpG dinucleotides, but are also found at non-CpG sites (CpA, CpT, and CpC). The general functions of CpG and non-CpG methylation include gene silencing or activation depending on the methylated regions.
Hyun Jang, Woo Shin, Jeong Lee, Jeong Do
openaire   +3 more sources

TLR9-mediated activation of dendritic cells by CD32 targeting for the generation of highly immunostimulatory vaccines

Human Vaccines & Immunotherapeutics, 2019
The rational for designing dendritic cell (DC)-targeted immunotherapies is their central role in orchestrating immunity. Most studies addressing antigen-targeting to DCs for eliciting T cell responses have employed ex-vivo matured DCs derived from ...
J. A. Sepulveda-Toepfer, Johannes Pichler, Kathrin Fink, Milica Sevo, Sonja Wildburger, Liesbeth Christiene Mudde-Boer, Christopher Taus, Geert Cornelius Mudde   +7 more
doaj   +1 more source

Estimation of fracture half-length with fast Gaussian pressure transient and RTA methods: Wolfcamp shale formation case study

Journal of Petroleum Exploration and Production Technology, 2023
Accurate estimation of fracture half-lengths in shale gas and oil reservoirs is critical for optimizing stimulation design, evaluating production potential, monitoring reservoir performance, and making informed economic decisions.
Ahmed Farid Ibrahim, Ruud Weijermars
doaj   +1 more source

Malaysian clinical practice guidelines for management of diabetic foot: A synopsis for the primary care physician [PDF]

Malaysian Family Physician, 2021
Diabetic foot requires careful attention and coordinated management by a dedicated team. Screening, prevention, adequate assessment, and appropriate referral are crucial to prevent complications. Multimodal treatment and rehabilitation are recommended to
Thiruselvam Tharumaraja, Aminudin Che-Ahmad, Ping Foo Wong, Afiza Hanun Ahmad@Hamid, Mohd Idham Hasan, Mohd Yazid Bajuri, Gurmeet Singh Sewa Singh, Vijiya Mala Valayatham, Siti Norzalilah Abdul Majid, Hafizan Mohd Tajri, Masfiza Abdul Hamid, Ainol Haniza Kherul Anuwar, Mohd Aminuddin Mohd Yusof   +12 more
doaj   +1 more source

Integrating Contact-aware Feedback CPG System for Learning-based Soft Snake Robot Locomotion Controllers [PDF]

arXiv, 2023
This paper aims to solve the contact-aware locomotion problem of a soft snake robot by developing bio-inspired contact-aware locomotion controllers. To provide effective contact information for the controllers, we develop a scale-covered sensor structure mimicking natural snakes' scale sensilla.
arxiv  

AIE‐based drug/gene delivery system: Evolution from fluorescence monitoring alone to augmented therapeutics

Aggregate, Volume 3, Issue 6, December 2022., 2022
The aggregation‐induced emission luminogens (AIEgens) propel the development of drug and gene delivery systems. The lit‐up AIEgens first serve for real‐time monitoring of the delivery processes and evaluation of therapeutic responses of drug/gene. The delicate design of AIEgens to form high‐level structural carrier remarkably enhances the delivery ...
Jie Sun, Xuewen He
wiley   +1 more source

Enxerto autógeno de crista ilíaca na reconstrução do processo alveolar em portadores de fissura labiopalatina: estudo de 30 casos

Revista do Colégio Brasileiro de Cirurgiões
A reconstrução do processo alveolar em pacientes portadores de fissuras labiopalatais (FLP) é fundamental para erupção de dentes permanentes e para o restabelecimento estético através de implantes osteointegrados.
João Luiz Carlini, André Luís Zétola, Ricardo Pires de Souza, Odilon Victor Porto Denardin, Abrão Rapoport   +4 more
doaj   +1 more source

Prediction of CpG-island function: CpG clustering vs. sliding-window methods [PDF]

BMC Genomics, 2010
Unmethylated stretches of CpG dinucleotides (CpG islands) are an outstanding property of mammal genomes. Conventionally, these regions are detected by sliding window approaches using %G + C, CpG observed/expected ratio and length thresholds as main parameters.
Michael Hackenberg, José L. Oliver, Pedro L. Luque-Escamilla, Guillermo Barturen, Christopher Previti, Pedro Carpena, Pedro Carpena   +6 more
openaire   +6 more sources

Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements [PDF]

, 2013
Background: Recent assays for individual-specific genome-wide DNA methylation profiles have enabled epigenome-wide association studies to identify specific CpG sites associated with a phenotype. Computational prediction of CpG site-specific methylation levels is important, but current approaches tackle average methylation within a genomic locus and are
arxiv   +1 more source

Distribution of DNA methylation, CpGs, and CpG islands in human isochores

Genomics, 2010
DNA methylation is a major epigenetic modification of the genome that affects basic biological functions, such as gene expression and cell development. We used the human genome sequences and the DNA methylation data that are available in order to establish a map of the levels of GC and methylation in isochores.
Annalisa Varriale, Giorgio Bernardi
openaire   +3 more sources