Results 41 to 50 of about 370,062 (234)
Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus [PDF]
, 1996 The methyl-CpG binding domain (MBD) proteins are key molecules in the interpretation of DNA methylation signals leading to gene silencing. We investigated their binding specificity at the constitutively methylated region of a CpG island containing the ...
Auriol, Emilie +3 more
core +2 more sources
Epigenetics, 2022 DNA methylation (DNAm) in mammals is mostly examined within the context of CpG dinucleotides. Non-CpG DNAm is also widespread across the human genome, but the functional relevance, tissue-specific disposition, and inter-individual variability has not ...
Philip Titcombe +10 more
doaj +1 more source
MethodsX, 2022 Clastic reservoir core is routinely characterized using conventional, destructive spot sampling techniques. Whilst spot sampling provides useful textural and compositional information, the samples are typically widely spaced (∼ 25 cm), and hence ...
Arif Hussain, Khalid Al-Ramadan
doaj +1 more source
Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. [PDF]
, 2018 OBJECTIVE:Epigenetic modifications have previously been associated with rheumatoid arthritis (RA). In this study, we aimed to determine whether differential DNA methylation in peripheral blood cell subpopulations is associated with any of 4 clinical ...
Barcellos, Lisa F +13 more
core +1 more source
Human Vaccines & Immunotherapeutics, 2023 COVID-19 pandemic caused by SARS-CoV-2 infection has an impact on global public health and social economy. The emerging immune escape of SARS-CoV-2 variants pose great challenges to the development of vaccines based on original strains.
Feixia Gao +10 more
doaj +1 more source
Exploring genome wide bisulfite sequencing for DNA methylation analysis in livestock: a technical assessment [PDF]
, 2014 peer-reviewedRecent advances made in “omics” technologies are contributing to a revolution in livestock selection and breeding practices. Epigenetic mechanisms, including DNA methylation are important determinants for the control of gene expression in ...
Couldrey, Christine, Doherty, Rachael
core +2 more sources
CpG-Based Nanovaccines for Cancer Immunotherapy
International Journal of Nanomedicine, 2021 Wenqiang Chen,1 Mingxia Jiang,1 Wenjing Yu,1 Zhiwei Xu,1 Xinyue Liu,1 Qingmiao Jia,1 Xiuwen Guan,1– 3 Weifen Zhang1– 3 1College of Pharmacy, Weifang Medical University, Weifang, 261053, People’s Republic of China; 2Collaborative Innovation Center for ...
Chen W +7 more
doaj
Workflow for Probabilistic Resource Estimation: Jafurah Basin Case Study (Saudi Arabia)
Energies, 2021 This study provides a workflow and preliminary estimations of the estimated ultimate recovery (EUR) volumes for natural gas and condensate liquids in the Tuwaiq Mountain Formation, the principal target in the Jafurah Field development project in Saudi ...
Ruud Weijermars +2 more
doaj +1 more source
Identification of CpG islands using a bank of IIR lowpass filters [PDF]
, 2004 It has been known that biological sequences such as the DNA sequence display different kinds of patterns depending on their biological functions. This statistical difference can be exploited for identifying the region of interest, such as the protein ...
Vaidyanathan, P. P., Yoon, Byung-Jun
core
Building solids inside nano-space: from confined amorphous through confined solvate to confined ‘metastable’ polymorph [PDF]
, 2015 The nanocrystallisation of complex molecules inside mesoporous hosts and control over the resulting structure is a significant challenge. To date the largest organic molecule crystallised inside the nano-pores is a known pharmaceutical intermediate – ROY
Aceves-Hernandez +69 more
core +1 more source