Results 61 to 70 of about 370,062 (234)
Applied Computing and GeosciencesIndonesia, one of the most earthquake-prone countries in the world, is currently developing an Earthquake Early Warning (EEW) system. A key component of this system, the Regional EEW, relies on Ground Motion Prediction models (GMPMs) to issue end-user ...
Andy Rachmadan +2 more
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Фармакокинетика и Фармакодинамика, 2020 The technique of quantitative determination of GZK-111 and CPG compounds in rat blood plasma has been developed. The analysis was carried out using the combined method of high-performance liquid chromatography with mass spectrometric detection.
A. L. Podolko +6 more
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Embryo culture in presence of oviductal fluid induces DNA methylation changes in bovine blastocysts [PDF]
, 2017 During the transit through the oviduct, the early embryo initiates an extensive DNA methylation reprogramming of its genome. Given that these epigenetic modifications are susceptible to environmental factors, components present in the oviductal milieu ...
Barrera, Antonio Daniel +7 more
core +1 more source
Polycomb-like proteins link the PRC2 complex to CpG islands
Nature, 2017 The Polycomb repressive complex 2 (PRC2) mainly mediates transcriptional repression and has essential roles in various biological processes including the maintenance of cell identity and proper differentiation. Polycomb-like (PCL) proteins, such as PHF1,
Haojie Li +11 more
semanticscholar +1 more source
Solution structure of human MBD1 CXXC1 [PDF]
, 2015 No abstract ...
Smith, Brian O., Thomson, Ross
core +2 more sources
Nature Immunology, 2018 Macrophages enforce antitumor immunity by engulfing and killing tumor cells. Although these functions are determined by a balance of stimulatory and inhibitory signals, the role of macrophage metabolism is unknown.
Mingen Liu +5 more
semanticscholar +1 more source
Mutation dynamics of CpG dinucleotides during a recent event of vertebrate diversification
Epigenetics, 2019 DNA methylation in CpGs dinucleotides is associated with high mutability and disappearance of CpG sites during evolution. Although the high mutability of CpGs is thought to be relevant for vertebrate evolution, very little is known on the role of CpG ...
Fábio Pértille +7 more
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Immortalization of T-cells is accompanied by gradual changes in CpG methylation resulting in a profile resembling a subset of T-cell leukemias [PDF]
, 2014 We have previously described gene expression changes during spontaneous immortalization of T-cells, thereby identifying cellular processes important for cell growth crisis escape and unlimited proliferation. Here, we analyze the same model to investigate
Borssén, Magnus +10 more
core +1 more source
Nucleic Acids Research, 2019 Zinc finger antiviral protein (ZAP) is a powerful restriction factor for viruses with elevated CpG dinucleotide frequencies. We report that ZAP similarly mediates antiviral restriction against echovirus 7 (E7) mutants with elevated frequencies of UpA ...
V. Odon +7 more
semanticscholar +1 more source
Establishment of Clinical Policy Making in Iran [PDF]
Patient Safety and Quality Improvement Journal, 2014 The worldwide increase in the cost of health services has now become a shared concern for all health managers and experts. Regarding the limited allocatable resources to hygiene and treatment systems and numerous needs in this section, both the ...
Shirvani A +3 more
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