Results 61 to 70 of about 164,159 (291)

Induction of Robust Immune Responses by CpG-ODN-Loaded Hollow Polymeric Nanoparticles for Antiviral and Vaccine Applications in Chickens

open access: yesInternational Journal of Nanomedicine, 2020
Shu-Yi Lin,1 Bing-Yu Yao,2 Che-Ming Jack Hu,2,3 Hui-Wen Chen1,3 1Department of Veterinary Medicine, National Taiwan University, Taipei, Taiwan; 2Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; 3Research Center for Nanotechnology and ...
Lin SY, Yao BY, Hu CMJ, Chen HW
doaj  

Encapsidated-CpG ODN enhances immunogenicity of porcine circovirus type 2 virus-like particles

open access: hybrid, 2022
Payuda Hansoongnern   +8 more
openalex   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

SARS-CoV-2 hot-spot mutations are significantly enriched within inverted repeats and CpG island loci [PDF]

open access: hybrid, 2020
Pratik Goswami   +10 more
openalex   +1 more source

Precise Regulation of Membrane Proteins: From Physical Technology to Biomolecular Strategy

open access: yesAdvanced Science, EarlyView.
This review summarizes the emerging strategies for the precise regulation of membrane proteins using physical stimuli and biomolecule‐based tools. These methods provide new insights into cell regulation and offer promising directions for future disease treatment.
Xiu Zhao   +6 more
wiley   +1 more source

Epigenetic insights into mastitis in Mediterranean Italian River buffalo using nanopore sequencing

open access: yesItalian Journal of Animal Science
Mastitis represents one of the main challenges in dairy buffalo farming, with significant implications for animal health, milk quality, and farm profitability.
Ilaria Cascone   +10 more
doaj   +1 more source

Structural Insights into Methylated DNA Recognition by the Methyl-CpG Binding Domain of MBD6 from Arabidopsis thaliana [PDF]

open access: gold, 2022
Yutaka Mahana   +5 more
openalex   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

open access: yesAdvanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He   +17 more
wiley   +1 more source

Correction to: Probabilistic estimation of hydraulic fracture half-lengths: validating the Gaussian pressure-transient method with the traditional rate transient analysis-method (Wolfcamp case study)

open access: yesJournal of Petroleum Exploration and Production Technology, 2023
Dandi Alvayed   +5 more
doaj   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

open access: yesAdvanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei   +9 more
wiley   +1 more source

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