Results 71 to 80 of about 152,781 (323)
Mutation dynamics of CpG dinucleotides during a recent event of vertebrate diversification
Epigenetics, 2019 DNA methylation in CpGs dinucleotides is associated with high mutability and disappearance of CpG sites during evolution. Although the high mutability of CpGs is thought to be relevant for vertebrate evolution, very little is known on the role of CpG ...
Fábio Pértille +7 more
doaj +1 more source
Фармакокинетика и Фармакодинамика, 2020 The technique of quantitative determination of GZK-111 and CPG compounds in rat blood plasma has been developed. The analysis was carried out using the combined method of high-performance liquid chromatography with mass spectrometric detection.
A. L. Podolko +6 more
doaj +1 more source
Review: CPG as a controller for biomimetic floating robots [PDF]
arXiv, 2021 All vertebrates are capable of performing various types of physical activity. Locomotor patterns are created by the cyclical coordinated work of the skeletal muscles. The organization of such a system in living organisms is responsible for networks of interconnected populations of neurons capable of forming rhythmic activity - CPG.
arxiv
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie +4 more
wiley +1 more source
Diffusive Mass Transfer and Gaussian Pressure Transient Solutions for Porous Media
Fluids, 2021 This study revisits the mathematical equations for diffusive mass transport in 1D, 2D and 3D space and highlights a widespread misconception about the meaning of the regular and cumulative probability of random-walk solutions for diffusive mass transport.
Ruud Weijermars
doaj +1 more source
ASEAN Heart Journal, 2014 1Senior Consultant Cardiologist, National Heart Institute Kuala Lumpur 2Consultant Cardiologist, Subang Jaya Medical Centre, Selangor 3Consultant Cardiologist, Sarawak General Hospital Heart Centre 4Consultant Physician, Hospital Raja Permaisuri Bainun, Ipoh 5Consultant Cardiologist, Subang Jaya Medical Centre, Selangor 6Family Medicine Specialist ...
Nurul Aida Salleh +10 more
openaire +1 more source
Inorganic Nanomaterials Meet the Immune System: An Intricate Balance
Advanced Healthcare Materials, EarlyView.Metal nanomaterials influence the immune responses, such as cytokine production and T‐cell activity. Unintended immune modulation can have significant consequences while its fine‐tuning may transform the oncology care. Within this review, a critical analysis is offered regarding the nano/immune‐interaction and suggests the future research directions to
Gloria Pizzoli +3 more
wiley +1 more source
Pharmacogenomics and Personalized Medicine, 2023 Pingyi Wang,1– 3 Hongyan Lu,1– 3 Hao Rong,1– 3 Yuhe Wang,1– 4 Li Wang,1– 3 Xue He,1– 3 Dongya Yuan,1– 3 Yongjun He,1– 3 Tianbo Jin1– 3 1Key Laboratory of Molecular Mechanism and Intervention Research for Plateau Diseases of Tibet Autonomous Region ...
Wang P +8 more
doaj
Adjuvant Activity of CpG Oligodeoxynucleotides [PDF]
International Reviews of Immunology, 2006 Synthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs directly stimulate human B cells and plasmacytoid dendritic cells (pDCs), thereby promoting the production of Th1 and proinflammatory cytokines and the maturation/activation of professional antigen-presenting cells.
openaire +4 more sources
Immunopharmacology of CpG Oligodeoxynucleotides and Ribavirin [PDF]
Antimicrobial Agents and Chemotherapy, 2004 ABSTRACT To investigate their potential mechanisms of action, the nucleoside analogue ribavirin and a TLR9 agonist were compared. The CpG oligodeoxynucleotides (ODN) demonstrated strong TLR9-related Th1-type effects, and ribavirin appeared only to mediate signaling in TLR-transfected cells.
Arthur M. Krieg +8 more
openaire +2 more sources