Results 141 to 150 of about 869,007 (330)

Placental and Cord Blood DNA Methylation Changes Associated With Gestational Diabetes Mellitus in a Marginalized Population: The Untold Role of Saturated Fats

open access: yesMolecular Nutrition &Food Research, EarlyView.
Excessive intake of saturated fats during pregnancy is associated with DNA hypomethylation in placental and cord blood samples from women affected with gestational diabetes mellitus (GDM), impacting, in particular, the cord blood promoter of ZFP57, a key regulator of early embryonic epigenetic programming.
Fatima Ahmad   +13 more
wiley   +1 more source

DNA hypermethylation of COL4A1 in ultraviolet-B-induced age-related cataract models in vitro and in vivo [PDF]

open access: yesInternational Journal of Ophthalmology
AIM: To explore the DNA methylation of COL4A1 in ultraviolet-B (UVB)-induced age-related cataract (ARC) models in vitro and in vivo. METHODS: Human lens epithelium B3 (HLEB3) cells and Sprague Dawley rats were exposure to UVB respectively.
Li Wang   +7 more
doaj   +1 more source

Analysis of human chromosome 21: correlation of physical and cytogenetic maps; gene and CpG island distributions. [PDF]

open access: bronze, 1990
K. Gardiner   +7 more
openalex   +1 more source

Modeling fire‐related smoke inhalation injury using the human lung‐on‐a‐chip and organoid platform: Pathogenesis insights and therapeutic evaluation

open access: yesVIEW, EarlyView.
Fire‐related smoke inhalation‐induced acute lung injury (SI‐ALI) poses a significant public health risk, yet effective treatments are limited due to the lack of suitable models. This study developed a more realistic model of SI‐ALI using organ‐on‐a‐chip and organoid technologies, identified key molecules such as catechol‐O‐methyltransferase and ...
Junmin Li   +12 more
wiley   +1 more source

CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome?

open access: yesBMC Bioinformatics, 2009
Background CpG islands (CGIs), clusters of CpG dinucleotides in GC-rich regions, are often located in the 5' end of genes and considered gene markers. Hackenberg et al.
Han Leng, Zhao Zhongming
doaj   +1 more source

MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain. [PDF]

open access: yesNat Commun, 2023
Becht DC   +18 more
europepmc   +1 more source

Topology of Central Pattern Generators: Selection by Chaotic Neurons [PDF]

open access: yesarXiv, 1999
Central Pattern Generators (CPGs) in invertebrates are comprised of networks of neurons in which every neuron has reciprocal connections to other members of the CPG. This is a ``closed'' network topology. An ``open'' topology, where one or more neurons receives input but does not send output to other member neurons, is not found in these CPGs.
arxiv  

CpG Islands in Chromatin Organization and Gene Expression [PDF]

open access: bronze, 1999
Tapas K. Kundu   +1 more
openalex   +1 more source

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