Results 151 to 160 of about 71,046 (242)
CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers. [PDF]
BMC Bioinformatics, 2022 Maruyama O +5 more
europepmc +1 more source
Integration of epigenetics into ecotoxicology: insights and fundamental research needs
Biological Reviews, Volume 101, Issue 2, Page 826-847, April 2026.ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto +3 more
wiley +1 more source
Loss of EphA7 Expression in Basal Cell Carcinoma by Hypermethylation of CpG Islands in the Promoter Region. [PDF]
Anal Cell Pathol (Amst), 2022 Liu J +6 more
europepmc +1 more source
Cancer Science, Volume 117, Issue 4, Page 943-957, April 2026.ZNF844 functions as a tumor suppressor in NPC by inhibiting invasion and metastasis through regulation of the PI3K‐AKT signaling pathway. It may serve as a promising therapeutic target and prognostic biomarker for NPC. ABSTRACT Epigenetic regulation plays a crucial role in the development of nasopharyngeal carcinoma (NPC).
Jinping Xu +7 more
wiley +1 more source
Molecular Ecology, Volume 35, Issue 7, April 2026.ABSTRACT Epigenomic changes are a hallmark of aging, and DNA methylation (DNAm) has emerged as the most reliable molecular marker of an individual's age. Genome‐wide patterns of age‐associated hypo‐ and hypermethylation have been applied to generate predictive models (i.e., “epigenetic clocks”) capable of estimating chronological age in an increasingly
Samantha L. Bock +25 more
wiley +1 more source
Misexpression of genes lacking CpG islands drives degenerative changes during aging. [PDF]
Sci Adv, 2021 Lee JY +7 more
europepmc +1 more source
Experimental Physiology, Volume 111, Issue 4, Page 1708-1717, 1 April 2026.Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir +5 more
wiley +1 more source
Profiling selective binding to promoter CpG islands by a single-DNA mechanical footprinting assay. [PDF]
Biophys J, 2021 Huang W, Yan J.
europepmc +1 more source