Inhibitory effect of alpinetin on IL‐6 expression by promoting cytosine methylation in CpG islands in the IL‐6 promoter region [PDF]
Molecular Genetics & Genomic Medicine, 2020 Background Alpinetin is a flavonoid which exerts antibacterial and anti‐inflammatory functions. In order to prove that the induced methylation is an important mechanism for alpinetin in regulating the expression of inflammatory factor Interleukin‐6 (IL‐6)
Ke Hu +8 more
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Extensive sequence-influenced DNA methylation polymorphism in the human genome [PDF]
Epigenetics & Chromatin, 2010 Background Epigenetic polymorphisms are a potential source of human diversity, but their frequency and relationship to genetic polymorphisms are unclear.
Hellman Asaf, Chess Andrew
doaj +4 more sources
CpG Methylation Altered the Stability and Structure of the i-Motifs Located in the CpG Islands [PDF]
International Journal of Molecular Sciences, 2022 Kaori Tsukakoshi, Kazunori Ikebukuro
exaly +2 more sources
DNA binding by polycomb-group proteins: searching for the link to CpG islands [PDF]
Nucleic Acids Research, 2022 Chen Davidovich
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Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells [PDF]
Stem Cell Reports, 2021 David Lopez +2 more
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CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure. [PDF]
PLoS Genetics, 2006 CpG island methylation plays an important role in epigenetic gene control during mammalian development and is frequently altered in disease situations such as cancer.
Christoph Bock +5 more
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Genome Research, 1997 We describe an analysis of the CpG islands (CGIs) of the pig. We have used both database survey and a porcine genomic library that is enriched for CGIs. Approximately half of 41 pig genomic database sequences had CGIs with an average G + C content of 65.3%, an average CpG observed/expected frequency of 0.85, and an average size of 978 bp.
McQueen, H A +4 more
openaire +3 more sources
Comparative analysis of CpG islands among HBV genotypes. [PDF]
PLoS ONE, 2013 DNA methylation is being increasingly recognized to play a role in regulation of hepatitis B virus (HBV) gene expression. The aim of this study was to compare the CpG island distribution among different HBV genotypes.
Yongmei Zhang +11 more
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Particle swarm optimization with reinforcement learning for the prediction of CpG islands in the human genome. [PDF]
PLoS ONE, 2011 BACKGROUND: Regions with abundant GC nucleotides, a high CpG number, and a length greater than 200 bp in a genome are often referred to as CpG islands. These islands are usually located in the 5' end of genes.
Li-Yeh Chuang +3 more
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CpG islands undermethylation in human genomic regions under selective pressure. [PDF]
PLoS ONE, 2011 DNA methylation at CpG islands (CGIs) is one of the most intensively studied epigenetic mechanisms. It is fundamental for cellular differentiation and control of transcriptional potential.
Sergio Cocozza +3 more
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