Results 11 to 20 of about 487,995 (250)

CpG Islands of the Pig [PDF]

open access: yesGenome Research, 1997
We describe an analysis of the CpG islands (CGIs) of the pig. We have used both database survey and a porcine genomic library that is enriched for CGIs. Approximately half of 41 pig genomic database sequences had CGIs with an average G + C content of 65.3%, an average CpG observed/expected frequency of 0.85, and an average size of 978 bp.
McQueen, H A   +4 more
openaire   +5 more sources

Computational analysis of CpG site DNA methylation [PDF]

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Epigenetics is the study of factors that can change DNA and passed to next generation without change to DNA sequence.
Ghorbani, Mohammadmersad
core   +7 more sources

CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure. [PDF]

open access: yesPLoS Genetics, 2006
CpG island methylation plays an important role in epigenetic gene control during mammalian development and is frequently altered in disease situations such as cancer.
Christoph Bock   +5 more
doaj   +2 more sources

Comparative analysis of CpG islands among HBV genotypes. [PDF]

open access: yesPLoS ONE, 2013
DNA methylation is being increasingly recognized to play a role in regulation of hepatitis B virus (HBV) gene expression. The aim of this study was to compare the CpG island distribution among different HBV genotypes.
Yongmei Zhang   +11 more
doaj   +1 more source

Particle swarm optimization with reinforcement learning for the prediction of CpG islands in the human genome. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Regions with abundant GC nucleotides, a high CpG number, and a length greater than 200 bp in a genome are often referred to as CpG islands. These islands are usually located in the 5' end of genes.
Li-Yeh Chuang   +3 more
doaj   +1 more source

CpG islands undermethylation in human genomic regions under selective pressure. [PDF]

open access: yesPLoS ONE, 2011
DNA methylation at CpG islands (CGIs) is one of the most intensively studied epigenetic mechanisms. It is fundamental for cellular differentiation and control of transcriptional potential.
Sergio Cocozza   +3 more
doaj   +1 more source

A Hybrid Approach for CpG Island Detection in the Human Genome. [PDF]

open access: yesPLoS ONE, 2016
BACKGROUND:CpG islands have been demonstrated to influence local chromatin structures and simplify the regulation of gene activity. However, the accurate and rapid determination of CpG islands for whole DNA sequences remains experimentally and ...
Cheng-Hong Yang   +3 more
doaj   +1 more source

Defining the protein complement of CpG islands [PDF]

open access: yes, 2011
In higher eukaryotes, the DNA base Cytosine can exist in a variety of modified forms when in the dinucleotide CpG. Although a methylated form tends to dominate within the genome, approximately 1% of all CpG dinucleotides are found unmodified at high ...
Thomson, John Paterson
core   +3 more sources

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