Genome Research, 1997 We describe an analysis of the CpG islands (CGIs) of the pig. We have used both database survey and a porcine genomic library that is enriched for CGIs. Approximately half of 41 pig genomic database sequences had CGIs with an average G + C content of 65.3%, an average CpG observed/expected frequency of 0.85, and an average size of 978 bp.
McQueen, H A +4 more
openaire +4 more sources
CpG islands undermethylation in human genomic regions under selective pressure. [PDF]
PLoS ONE, 2011 DNA methylation at CpG islands (CGIs) is one of the most intensively studied epigenetic mechanisms. It is fundamental for cellular differentiation and control of transcriptional potential.
Sergio Cocozza +3 more
doaj +2 more sources
Comparative analysis of CpG islands among HBV genotypes. [PDF]
PLoS ONE, 2013 DNA methylation is being increasingly recognized to play a role in regulation of hepatitis B virus (HBV) gene expression. The aim of this study was to compare the CpG island distribution among different HBV genotypes.
Yongmei Zhang +11 more
doaj +2 more sources
Intergenic, gene terminal, and intragenic CpG islands in the human genome
BMC Genomics, 2010 Background Recently, it has been discovered that the human genome contains many transcription start sites for non-coding RNA. Regulatory regions related to transcription of this non-coding RNAs are poorly studied.
Kulakovskiy Ivan V +7 more
doaj +2 more sources
Evolution of CpG-islands by means of tandem duplications
Вавиловский журнал генетики и селекции, 2017 CG-rich islands (CpG-islands, or CGI) are important functional elements in a genome of vertebrates. In particular, they: a) initiate transcription as promoters in most (> 50 %) genes of vertebrates, in some cases bi-directional, due to self-complement
V. N. Babenko +4 more
doaj +3 more sources
CpG Methylation Altered the Stability and Structure of the i-Motifs Located in the CpG Islands [PDF]
International Journal of Molecular Sciences, 2022 Kaori Tsukakoshi +2 more
exaly +2 more sources
DNA binding by polycomb-group proteins: searching for the link to CpG islands [PDF]
Nucleic Acids Research, 2022 Chen Davidovich, Davidovich Chen
exaly +2 more sources
Species-Specific Relationships between DNA and Chromatin Properties of CpG Islands in Embryonic Stem Cells and Differentiated Cells [PDF]
Stem Cell Reports, 2021 David Lopez +2 more
exaly +2 more sources
CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure. [PDF]
PLoS Genetics, 2006 CpG island methylation plays an important role in epigenetic gene control during mammalian development and is frequently altered in disease situations such as cancer.
Christoph Bock +5 more
doaj +2 more sources
Particle swarm optimization with reinforcement learning for the prediction of CpG islands in the human genome. [PDF]
PLoS ONE, 2011 BACKGROUND: Regions with abundant GC nucleotides, a high CpG number, and a length greater than 200 bp in a genome are often referred to as CpG islands. These islands are usually located in the 5' end of genes.
Li-Yeh Chuang +3 more
doaj +1 more source