Results 91 to 100 of about 2,267 (171)

Number of embryos injected with the cpsf6 mRNA.

, 2017
Number of embryos injected with the cpsf6 mRNA.
Takao Sasado (24195), Makoto Furutani-Seiki (24192), Hisato Kondoh (24197), Kiyoshi Naruse (247054)   +3 more
core   +1 more source

Data_Sheet_1_Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3′UTR in Gastric Cancer Cells.PDF

, 2021
Alternative polyadenylation (APA) is an important RNA post-transcriptional process, which can generate diverse mRNA isoforms. Increasing evidence shows that APA is involved in cell self-renewal, development, immunity, and cancer. CPSF6 is one of the core
Jielin Sun (123338), Keshuo Ding (10217677), Qiang Zhao (105948), Xinglong Shi (2551834), Pengxiao Li (11430004), Sheng Tan (431021), Yani Kang (698978)   +6 more
core   +1 more source

Drug PF-3450074 binds to part of the CPSF6-binding interface in HIV-1 CA^N.

, 2012
(A) Superposition of HIV-1 CAN:PF-3450074 structure (pdb: 2XDE) [38] on HIV-1 CAN:CPSF6313–327 using secondary structure matching of the HIV-1 CAN domains. Drug PF-3450074 is shown in cyan, CPSF6313–327 in yellow.
Vineet N. KewalRamani (138643), Leo C. James (138654), Torsten Schaller (138630), Tom Elliott (138636), Jason W. Chin (138646), Adam J. Fletcher (138624), KyeongEun Lee (138641), Greg J. Towers (138650), Amanda J. Price (138619)   +8 more
core   +1 more source

Table_1_Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3′UTR in Gastric Cancer Cells.DOCX

, 2021
Alternative polyadenylation (APA) is an important RNA post-transcriptional process, which can generate diverse mRNA isoforms. Increasing evidence shows that APA is involved in cell self-renewal, development, immunity, and cancer. CPSF6 is one of the core
Jielin Sun (123338), Keshuo Ding (10217677), Qiang Zhao (105948), Xinglong Shi (2551834), Pengxiao Li (11430004), Sheng Tan (431021), Yani Kang (698978)   +6 more
core   +1 more source

Quantitative microscopy of functional HIV post-entry complexes reveals association of replication with the viral capsid

eLife, 2014
The steps from HIV-1 cytoplasmic entry until integration of the reverse transcribed genome are currently enigmatic. They occur in ill-defined reverse-transcription- and pre-integration-complexes (RTC, PIC) with various host and viral proteins implicated.
Ke Peng, Walter Muranyi, Bärbel Glass, Vibor Laketa, Stephen R Yant, Luong Tsai, Tomas Cihlar, Barbara Müller, Hans-Georg Kräusslich   +8 more
doaj   +1 more source

Table_3_Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3′UTR in Gastric Cancer Cells.DOCX

, 2021
Alternative polyadenylation (APA) is an important RNA post-transcriptional process, which can generate diverse mRNA isoforms. Increasing evidence shows that APA is involved in cell self-renewal, development, immunity, and cancer. CPSF6 is one of the core
Jielin Sun (123338), Keshuo Ding (10217677), Qiang Zhao (105948), Xinglong Shi (2551834), Pengxiao Li (11430004), Sheng Tan (431021), Yani Kang (698978)   +6 more
core   +1 more source

Data_Sheet_2_Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3′UTR in Gastric Cancer Cells.PDF

, 2021
Alternative polyadenylation (APA) is an important RNA post-transcriptional process, which can generate diverse mRNA isoforms. Increasing evidence shows that APA is involved in cell self-renewal, development, immunity, and cancer. CPSF6 is one of the core
Jielin Sun (123338), Keshuo Ding (10217677), Qiang Zhao (105948), Xinglong Shi (2551834), Pengxiao Li (11430004), Sheng Tan (431021), Yani Kang (698978)   +6 more
core   +1 more source

Table_5_Suppression of CPSF6 Enhances Apoptosis Through Alternative Polyadenylation-Mediated Shortening of the VHL 3′UTR in Gastric Cancer Cells.XLSX

, 2021
Alternative polyadenylation (APA) is an important RNA post-transcriptional process, which can generate diverse mRNA isoforms. Increasing evidence shows that APA is involved in cell self-renewal, development, immunity, and cancer. CPSF6 is one of the core
Jielin Sun (123338), Keshuo Ding (10217677), Qiang Zhao (105948), Xinglong Shi (2551834), Pengxiao Li (11430004), Sheng Tan (431021), Yani Kang (698978)   +6 more
core   +1 more source

The CPSF6 interface is conserved in HIV-1, HIV-2, SIVmac CA^N.

, 2012
(A) The CPSF6-binding interface is highly conserved within HIV-1 viruses. The ConSurf Server [42], [43] was used to map ∼100 unique HIV-1 CAN sequences onto the HIV-1 CAN:CPSF6313–327 structure.
Vineet N. KewalRamani (138643), Leo C. James (138654), Torsten Schaller (138630), Tom Elliott (138636), Jason W. Chin (138646), Adam J. Fletcher (138624), KyeongEun Lee (138641), Greg J. Towers (138650), Amanda J. Price (138619)   +8 more
core   +1 more source

Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle

Summary Viruses rely on host cellular machinery for replication. After entering the nucleus, the HIV genome accumulates in nuclear niches where it undergoes reverse transcription and integrates into neighboring chromatin, promoting high transcription rates and new virus progeny.
Celine Cuche, Chiara Tomasini, Selen Ay, Maxence Collard, Bin Cui, Mohammad Rashid, Shaoni Bhattacharjee, Julian Buchrieser, Charlotte Luchsinger, Cinzia Bertelli, Vladimir N Uversky, Felipe Diaz-Griffero, Francesca Di Nunzio   +12 more
openaire   +1 more source