Results 81 to 90 of about 1,827 (136)

Retraction note to: RNA-binding protein CPSF6 regulates IBSP to affect pyroptosis in gastric cancer. [PDF]

World J Gastrointest Oncol
The authors have decided to retract the article published on World J Gastrointest Oncol (2023) for further consideration due to data errors and some misunderstandings in communication.
Wang XJ, Liu Y, Ke B, Zhang L, Liang H.
europepmc   +2 more sources

Analysis of CA Content and CPSF6 Dependence of Early HIV-1 Replication Complexes in SupT1-R5 Cells

mBio, 2019
The HIV-1 capsid performs essential functions during early viral replication and is an interesting target for novel antivirals. Thus, understanding molecular and structural details of capsid function will be important for elucidating early HIV-1 (and retroviral in general) replication in relevant target cells and may also aid antiviral development ...
Vojtech Zila, Thorsten G. Müller, Vibor Laketa, Barbara Müller, Hans-Georg Kräusslich   +4 more
openaire   +3 more sources

Disruption of CPSF6 enhances cellular permissivity to HIV-1 infection through alternative polyadenylation

Abstract Human immunodeficiency virus (HIV) relies upon a broad array of host factors in order to replicate and evade the host antiviral response1. Cleavage and polyadenylation specificity factor 6 (CPSF6) is one such host factor that is recruited by incoming HIV-1 cores to regulate trafficking2, nuclear import3-5, uncoating6, and integration ...
Judd Hultquist, Daphne Cornish, Kathryn Jackson-Jones, Ted Ling-Hu, Lacy Simons, William Cisneros, Edmund Kuffour, Francesca Agnes, Yujin Lee, Paul Bieniasz, Ramon Lorenzo-Redondo   +10 more
openaire   +2 more sources

Inhibiting circ_0000673 blocks the progression of colorectal cancer through downregulating CPSF6 via targeting miR-548b-3p

Advances in Clinical and Experimental Medicine
Colorectal cancer (CRC) is one of the most common cancers, and its progression is regulated by several factors, including circular RNA (circRNA).The objective of this study was to determine the role, or roles, of circ_0000673 in CRC.We used quantitative real-time polymerase chain reaction (qPCR) to detect the expression of circ_0000673, miR-548b-3p and
Shuang, Li, Tuoyun, Yang, Lu, Liu, Baorong, Hu, Xi, Chen, Wenting, Zhao, Xin, Hai   +6 more
openaire   +2 more sources

Cleavage and polyadenylation specific factor 6 (CPSF6); cyclophilin A (CYPA; PPIA) [PDF]

Science-Business eXchange, 2013
openaire   +1 more source

3'UTR Mapping Reveals Alternative Polyadenylation in Right Ventricular Failure. [PDF]

Circ Res
Neupane R, Natarajan K, Suarez EE, Pownall HJ, Huang KL, Wagner EJ, Verma AK, Majji R, Yalamanchili HK, Guha A, Thandavarayan RA.   +10 more
europepmc   +1 more source

Alternative polyadenylation links RNA processing to iron metabolism in human erythropoiesis. [PDF]

Nucleic Acids Res
Yu S, Zeng X, Chen J, Lou Z, Jiang T, Ou Y, Du P, Rao J, Dai X, Gong M, Xu J, Yi P, Wang F, Wang X, Zhu Y.   +14 more
europepmc   +1 more source

Lenacapavir-induced capsid damage uncovers HIV-1 genomes emanating from nuclear speckles. [PDF]

EMBO J
Müller TG, Klaus S, Zila V, Lucic B, Penzo C, Nopper SL, Golani G, Anders-Össwein M, Sonntag-Buck V, Heuser AM, Schwarz US, Laketa V, Lusic M, Müller B, Kräusslich HG.   +14 more
europepmc   +1 more source

CRISPR/Cas9 screening with destabilized bicistronic fluorescent protein reporter revealed PABPN1 as a hub of regulators for alternative polyadenylation. [PDF]

Nucleic Acids Res
Hu Z, Liu Y, Han Y, Li M, Deng K, Lu X, Huang Y, Liang C, Wang Y, Fu Y, Xu A.   +10 more
europepmc   +1 more source

Nuclear pore passage of the HIV capsid is driven by its unusual surface amino acid composition. [PDF]

Nat Struct Mol Biol
Fu L, Cheng S, Riedel D, Kopecny L, Schuh M, Görlich D.   +5 more
europepmc   +1 more source