Results 221 to 230 of about 26,802 (257)

Equine botulism

open access: yesEquine Veterinary Journal, Volume 58, Issue 2, Page 333-347, March 2026.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik   +2 more
wiley   +1 more source

Harnessing blue light photobiomodulation for cancer therapy: Evidence from a systematic review

open access: yesPhotochemistry and Photobiology, Volume 102, Issue 2, Page 370-399, March/April 2026.
Conventional treatments for various types of cancer are often associated with tumor recurrence and aggressiveness. Photobiomodulation with blue light (BL; 450–470 nm) emerges as a promising alternative with antitumor effects. This systematic review, with 37 in vitro and in vivo studies from 2002 to 2024, revealed that BL reduces cell viability ...
Bárbara Evelyn Santos de Lima   +6 more
wiley   +1 more source

Optimal neuromuscular performance requires motor neuron phosphagen kinases

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 2027-2059, 1 March 2026.
Abstract figure legend Motor neuron (MN) terminals in fruit flies, mice and humans contain phosphagen kinases, a key enzyme in their energy storage and buffering system. Here we knocked down the primary phosphagen kinase in fruit fly larvae (arginine kinase 1 (ArgK1)) but were surprised to find that MN endurance was unaffected.
Karlis A. Justs   +10 more
wiley   +1 more source

Dynamic balance of myoplasmic energetics, redox state and protons in a fast‐twitch oxidative glycolytic skeletal muscle fibre

open access: yesThe Journal of Physiology, Volume 604, Issue 5, Page 1840-1871, 1 March 2026.
Abstract figure legend We have developed a computational model of energy metabolism in fast‐twitch oxidative glycolytic muscle fibres. The model considers thermodynamically constrained enzyme kinetics derived from in vitro data and was validated against in vivo data from phosphorus magnetic resonance spectroscopy.
Jana Disch   +4 more
wiley   +1 more source

Connectomic and behavioral alterations in creatine transporter deficiency are partially normalized by gene therapy

open access: yes
Montani C   +17 more
europepmc   +1 more source

Processing of mitochondrial precursor proteins [PDF]

open access: yes, 1984
Neupert, Walter, Schmidt, Bernd
core  

RESPONSE TO CREATINE ANALOGOUS SUPPLEMENTATION IN CREATINE TRANSPORTER DEFICIENCY

open access: yes, 2009
Campistol-Plana J   +7 more
openaire   +2 more sources
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Creatine transport and pathological changes in creatine transporter deficient mice

Journal of Inherited Metabolic Disease, 2021
AbstractThe severe impact on brain function and lack of effective therapy for patients with creatine (Cr) transporter deficiency motivated the generation of three ubiquitous Slc6a8 deficient mice (−/y). While each mouse knock‐out line has similar behavioral effects at 2 to 3 months of age, other features critical to the efficient use of these mice in ...
Adam M. Wawro   +5 more
openaire   +2 more sources

Creatine and the creatine transporter: A review

Molecular and Cellular Biochemistry, 2001
The cellular role of creatine (Cr) and Cr phosphate (CrP) has been studied extensively in neural, cardiac and skeletal muscle. Several studies have demonstrated that alterations in the cellular total Cr (Cr + CrP) concentration in these tissues can produce marked functional and/or structural change.
Snow, Rodney., Murphy, Robyn Maree.
openaire   +2 more sources

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