Results 51 to 60 of about 83,279 (184)
CRISPR-Cas13a SHERLOCK assay for rapid and sensitive detection of chikungunya virus. [PDF]
Microbiol SpectrABSTRACT Chikungunya virus (CHIKV), a major cause of acute febrile illness and joint pain, remains a significant public health threat in tropical regions. Rapid and accurate detection is essential for timely clinical management and outbreak control, particularly in resource-limited settings ...
Athipanyasilp N +9 more
europepmc +4 more sources
CRISPR-Cas13a-based detection method for avian influenza virus
Frontiers in Microbiology, 2023 Avian influenza virus (AIV) causes huge losses to the global poultry industry and poses a threat to humans and other mammals. Fast, sensitive, and portable diagnostic methods are essential for efficient avian influenza control. Here, a clustered regularly interspaced short palindromic repeats (CRISPR)-Cas13a based platform was developed to detect AIV ...
Yuhan Wu +9 more
openaire +3 more sources
Cas6 specificity and CRISPR RNA loading in a complex CRISPR-Cas system [PDF]
, 2014 This research was funded in part by Biotechnology and Biological Sciences Research Council [BB/K000314/1]. The APC was paid through RCUK OA block grant funds.CRISPR-Cas is an adaptive prokaryotic immune system, providing protection against viruses and ...
Malcolm F. White +5 more
core +1 more source
CRISPR RNA biogenesis by a Cas6 nuclease [PDF]
, 2015 Clustered regularly interspaced short palindromic repeats (CRISPRs) and associated (Cas) proteins form the basis of a prokaryotic adaptive immune system.
Sokolowski, Richard D.
core +2 more sources
Biosensors, 2023 The rapid and ongoing spread of the coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emphasizes the urgent need for an easy and sensitive virus detection method.
Yao Han +9 more
doaj +1 more source
Structure of the archaeal Cascade subunit Csa5 : Relating the small subunits of CRISPR effector complexes [PDF]
, 2013 This work was funded by a grant from the Biotechnology and Biological Sciences Research Council (BBSRC) (REF: BB/G011400/1) to M.F.W. and J.H.N. and a BBSRC-funded studentship to J.R.The Cascade complex for CRISPR-mediated antiviral immunity uses CRISPR ...
Naismith, Jim +5 more
core +1 more source
Differentiation of Classical Swine Fever Virus Virulent and Vaccine Strains by CRISPR/Cas13a
Microbiology Spectrum, 2022 As a notifiable terrestrial and aquatic animal disease listed by World Organisation for Animal Health (formerly the Office International des Epizooties [OIE]), classical swine fever (CSF) has caused great economic losses to the swine industry worldwide ...
Yuhang Zhang +10 more
doaj +1 more source
Biogenesis pathways of RNA guides in archaeal and bacterial CRISPR-Cas adaptive immunity [PDF]
, 2015 EC is supported by the Alexander von Humboldt Foundation, the German Federal Ministry for Education and Research, the Helmholtz Association, the Göran Gustafsson Foundation, the Swedish Research Council, the Kempe Foundation and Umeå University.
White, Malcolm F. +4 more
core +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Journal of Microbiology, Immunology and Infection, 2022 Background: Rapid and reliable diagnostic methods for Aspergillus fumigatus infection are urgently needed. Clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 13a (Cas13a) has high sensitivity and specificity in the ...
Zhengtu Li +8 more
doaj +1 more source