Results 81 to 90 of about 83,279 (184)
Thermophoretic Aggregation Imaging of Tumor-Derived Exosomes by CRISPR-Cas13a-Based Nanoprobes
The inherent heterogeneity of tumor-derived exosomes holds great promise for enhancing the precision of cancer diagnostics. MicroRNAs (miRNAs) encapsulated in tumor-associated exosomes have emerged as valuable biomarkers for the early detection of ...
Na Li (6550) +5 more
core +1 more source
Establishing the CRISPR/Cas13a genome editing system in Nicotiana benthamiana for RNA targeting applications [PDF]
, 2021 Thesis (MScAgric)--Stellenbosch University, 2021.ENGLISH ABSTRACT: Globally, grapevine (Vitis vinifera) is a widely cultivated fruit crop and makes a vital contribution to the South African agricultural sector. Highly susceptible to a plethora of virus
Robertson, Gaëlle
core
Прямая детекция микроРНК mir-34a, -145 и -218 с помощью CRISPR/Cas13a-нуклеазы
, 2023 Using CRISPR/Cas13a-nuclease we have demonstrated a feasibility of direct detection of three miRNAs, miR-34a, -145, and -218 (their molecular signature is suggested as a diagnostic and prognostic biomarker in cervical cancer),. The detection is based on
Lisitsa, A.V. +5 more
core +1 more source
Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics
Drug Development Research, Volume 87, Issue 5, August 2026.ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba +2 more
wiley +1 more source
Electrochemical Science Advances, Volume 6, Issue 4, August 2026.ABSTRACT Rapid and sensitive detection of disease‐related biomarkers is critical for early diagnosis and appropriate treatment. However, conventional analytical methods are often time‐consuming and require complex procedures and skilled personnel.
Minju Ahn +4 more
wiley +1 more source
Erratum: Advances in application of CRISPR-Cas13a system
Frontiers in Cellular and Infection Microbiology[This corrects the article DOI: 10.3389/fcimb.2024.1291557.].
openaire +3 more sources
Journal of Clinical Laboratory Analysis, Volume 40, Issue 16, August 2026.A laboratory‐customized, open‐sequence TaqMan‐MGB probe assay was developed for detecting CYP2C19*2 and CYP2C19*17 polymorphisms using dried blood spot‐derived DNA. The assay demonstrated allele‐specific discrimination, candidate LODs of 1.17 × 102 copies/μL for CYP2C19*2 and 0.94 × 103 copies/μL for CYP2C19*17, and repeatability with CVs below 10%. In
Yaqun Liu +7 more
wiley +1 more source
Journal of Analytical Science and TechnologyThe abnormally expressed microRNAs (miRNAs) serve as crucial indicators for disease diagnosis and are strongly associated with the progression of various diseases.
Yunxiao Li, Qiuxia Wang, Yali Wang
doaj +1 more source
Lipid Nanoparticle-Mediated CRISPR-Cas13a Delivery for the Control of Bacterial Infection. [PDF]
Adv Healthc MaterAbstractLipid nanoparticles (LNPs) can assist in the delivery of nucleic acid inside animal cells, as demonstrated by their use in COVID‐19 vaccine development. However, LNPs applicable to bacteria have not been reported. Here, the screening of 511 LNPs containing random combinations of different lipid components identified two LNPs, LNP 496 and LNP ...
Kim B +9 more
europepmc +3 more sources
A Rapid, Field‐Deployable Diagnostic Platform for Getah Virus Based on RT‐RAA and CRISPR EsCas13d
Microbial Biotechnology, Volume 19, Issue 8, August 2026.This study developed a rapid, one‐step, visual detection platform termed ROSVD by integrating RT‐RAA with CRISPR–EsCas13d, enabling simplified sample preparation, high‐sensitivity, on‐site detection of GETV within 30 min without the need for sophisticated equipment.
Liu Baoling +5 more
wiley +1 more source