Results 11 to 20 of about 216,936 (304)
Veterinarska stanica, 2021 CRISPR/Cas9 postala je snažna metoda za unošenje promjena u genom brojnih organizama. Prvi put otkriven u bakterijama kao dio prilagodljivog imunološkog sustava, CRISPR/Cas9 i njegove modificirane verzije u širokoj su uporabi u inženjeringu genoma i aktivaciji ili suzbijanju ekspresije gena.
Mimoune, Nora +5 more
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The Advance of CRISPR-Cas9-Based and NIR/CRISPR-Cas9-Based Imaging System [PDF]
Frontiers in Chemistry, 2021 The study of different genes, chromosomes and the spatiotemporal relationship between them is of great significance in the field of biomedicine. CRISPR-Cas9 has become the most widely used gene editing tool due to its excellent targeting ability.
Huanhuan Qiao +6 more
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Therapeutic applications of CRISPR-Cas9 gene editing [PDF]
Frontiers in Genome EditingCRISPR-Cas9 is a gene editing tool used extensively in biological research that is now making its way into clinical therapies. With the first CRISPR therapy obtaining approval by the United States’ Food and Drug Administration (FDA) in late 2023, we look
Aditya Bharti, Joann Mudge
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CRISPR/Cas9 Delivery System Engineering for Genome Editing in Therapeutic Applications
Pharmaceutics, 2021 The clustered regularly interspaced short palindromic repeats (CRISPR)/associated protein 9 (CRISPR/Cas9) systems have emerged as a robust and versatile genome editing platform for gene correction, transcriptional regulation, disease modeling, and ...
Hao Cheng, Feng Zhang, Yang Ding
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Veterinarska stanica, 2021 Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR- associated system (Cas) is a system that provides immunity to most prokaryoticorganisms against viral attacks and other foreign bodies. CRISPR systems consist of a scissor-like protein called Cas9 and a genetic GPS guide “The guide RNA”.
Mimoune, Nora +4 more
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Application of CRISPR/Cas9 Technology in Cancer Treatment: A Future Direction
Current Oncology, 2023 Gene editing, especially with clustered regularly interspaced short palindromic repeats associated protein 9 (CRISPR-Cas9), has advanced gene function science. Gene editing’s rapid advancement has increased its medical/clinical value.
Ali A. Rabaan +20 more
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CRISPR/CAS9 Technologies [PDF]
Journal of Bone and Mineral Research, 2017 ABSTRACT The Clustered Regularly Interspaced Palindromic Repeats (CRISPR)/CRISPR-associated protein (Cas) pathway is revolutionizing biological research. Modifications to this primitive prokaryotic immune system now enable scientists to efficiently edit DNA or modulate gene expression in living ...
Bart O, Williams, Matthew L, Warman
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Current applications and future perspective of CRISPR/Cas9 gene editing in cancer
Molecular Cancer, 2022 Clustered regularly interspaced short palindromic repeats (CRISPR) system provides adaptive immunity against plasmids and phages in prokaryotes. This system inspires the development of a powerful genome engineering tool, the CRISPR/CRISPR-associated ...
Si-Wei Wang +9 more
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CRISPR/Cas genome editing in grapevine: recent advances, challenges and future prospects
Fruit Research, 2022 The development of clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9 (CRISPR/Cas9) system has revolutionized genome editing and plant breeding. Applications of CRISPR/Cas9 technology in fruit crops, including grapevine,
Chong Ren, Yanping Lin, Zhenchang Liang
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CRISPR/Cas9 in Gastrointestinal Malignancies [PDF]
Frontiers in Cell and Developmental Biology, 2021 Gastrointestinal (GI) cancers such as colorectal cancer (CRC), gastric cancer (GC), esophageal cancer (EG), pancreatic duct adenocarcinoma (PDAC) or hepatocellular cancer (HCC) belong to the most commonly diagnosed types of cancer and are among the most frequent causes of cancer related death worldwide.
Jefremow, André +2 more
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