Results 11 to 20 of about 216,867 (346)
Microbiology Spectrum, 2022 Acinetobacter baumannii is a well-known human opportunistic pathogen in nosocomial infections, and the emergence of multidrug-resistant Acinetobacter baumannii has become a complex problem for clinical anti-infective treatments.
Yuhang Wang +8 more
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Biologie in unserer Zeit, 2018 Pflanzen können von einer Vielzahl an Pathogenen befallen werden, die schwerwiegende Krankheiten auslösen und besonders bei Nutzpflanzen zu starken Ernteverlusten beitragen. CRISPR/Cas‐Systeme verändern die Angriffsstellen dieser Pathogene hochpräzise, sodass ein Befall nicht mehr stattfinden kann – eine Entwicklung, die als Revolution in der ...
Patrick Schindele +2 more
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Molecules, 2022 The CRISPR-Cas system is a bacterial and archaea adaptive immune system and is a newly recognized mechanism for controlling antibiotic resistance gene transfer. Acinetobacter baumannii (A.
Tingting Guo +8 more
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Phage delivered CRISPR-Cas system to combat multidrug-resistant pathogens in gut microbiome.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022 The Host-microbiome interactions that exist inside the gut microbiota operate in a synergistic and abnormal manner. Additionally, the normal homeostasis and functioning of gut microbiota are frequently disrupted by the intervention of Multi-Drug ...
Arijit Nath +13 more
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Adaptation in CRISPR-Cas Systems [PDF]
Molecular Cell, 2016 Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins constitute an adaptive immune system in prokaryotes. The system preserves memories of prior infections by integrating short segments of foreign DNA, termed spacers, into the CRISPR array in a process termed adaptation.
Samuel H. Sternberg +3 more
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CRISPR-Cas Systems in Streptococci [PDF]
Current Issues in Molecular Biology, 2019 Streptococci are one of the most important and common constituents of the host's microbiota and can colonize and live in the upper respiratory and urogenital tract of humans and animals. The CRISPR-Cas systems (i.e., clustered regularly interspaced short palindromic repeat, with CRISPR-associated proteins) found in bacteria and archaea provide sequence-
Tao, Gong +7 more
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The CRISPR/Cas System: A Customizable Toolbox for Molecular Detection
Genes, 2023 Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated proteins (Cas) are promising molecular diagnostic tools for rapidly and precisely elucidating the structure and function of genomes due to their high specificity ...
Yuxuan He +10 more
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New CRISPR-Cas systems discovered [PDF]
Cell Research, 2017 In bacteria and archaea, CRISPR-Cas adaptive immune systems utilize RNA-guided endonucleases to defend against invasion by foreign nucleic acids of bacteriophage, virus and plasmid origin. In a recent paper published in Nature, Burstein et al. identified the first Cas9 protein in uncultivated archaea and two novel CRISPR-CasX and CRISPR-CasY systems in
Hui, Yang, Dinshaw J, Patel
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CRISPR-Cas System: The Current and Emerging Translational Landscape
Cells, 2023 CRISPR-Cas technology has rapidly changed life science research and human medicine. The ability to add, remove, or edit human DNA sequences has transformative potential for treating congenital and acquired human diseases.
Narendranath Bhokisham +5 more
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Research advances on pathogenic nucleic acid detection technology based on CRIPSR/Cas system
浙江大学学报. 农业与生命科学版, 2023 Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) (CRISPR/Cas) system, an ancient bacterial and archaeal immune system, has rapidly developed into a popular gene-editing tool, which largely promotes the ...
LI Hongzhao +4 more
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