Development and Application of CRISPR/Cas System in Rice
Rice Science, 2019 In the past several years, the CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-associated protein) system has been harnessed as an efficient and powerful tool for targeted genome editing in different prokaryotic and ...
Ren Jun +3 more
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Genome editing with the CRISPR‐Cas system: an art, ethics and global regulatory perspective
Plant Biotechnology Journal, 2020 Summary Over the last three decades, the development of new genome editing techniques, such as ODM, TALENs, ZFNs and the CRISPR‐Cas system, has led to significant progress in the field of plant and animal breeding.
Debin Zhang +9 more
semanticscholar +1 more source
A Newly Discovered Bordetella Species Carries a Transcriptionally Active CRISPR-Cas with a Small Cas9 Endonuclease [PDF]
, 2015 Background Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated genes (cas) are widely distributed among bacteria.
Dudley, Edward G. +7 more
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Research progress of CRISPR/Cas systems in nucleic acid detection of infectious diseases
iLABMED, 2023 Infectious diseases are a serious threat to human health, and accurate, rapid and convenient early detection of pathogens is the first step of active treatment.
Jinying Dong, Yuguang Du, Lei Zhou
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Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system.
Cell, 2013 The spatiotemporal organization and dynamics of chromatin play critical roles in regulating genome function. However, visualizing specific, endogenous genomic loci remains challenging in living cells.
Baohui Chen +10 more
semanticscholar +1 more source
The CRISPR-Cas system as a tool for diagnosing and treating infectious diseases
Molecular Biology Reports, 2022 Emerging and relapsing infectious diseases pose a huge health threat to human health and a new challenge to global public health. Rapid, sensitive and simple diagnostic tools are keys to successful management of infectious patients and containment of ...
Juan Lou +8 more
semanticscholar +1 more source
Characterization of CRISPR-Cas Systems in Serratia marcescens Isolated from Rhynchophorus ferrugineus (Olivier, 1790) (Coleoptera: Curculionidae) [PDF]
, 2019 The CRISPR-Cas adaptive immune system has been attracting increasing scientific interest for biological functions and biotechnological applications. Data on the Serratia marcescens system are scarce.
Calia, Carla +7 more
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Research Progress on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-Associated Protein (Cas)-Isothermal Amplification in the Detection of Foodborne Pathogens [PDF]
Shipin KexueFood safety incidents caused by foodborne pathogens have attracted widespread attention. In order to ensure food safety, it is essential to adopt effective detection means.
ZHANG Qi, PANG Lidong, SU Qunchao, SONG Danliangmin, YANG Xinyan, JIANG Yujun, ZHANG Wei
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CRISPR/Cas9‐mediated genome editing: from basic research to translational medicine [PDF]
, 2020 The recent development of the CRISPR/Cas9 system as an efficient and accessible programmable genome-editing tool has revolutionized basic science research. CRISPR/Cas9 system-based technologies have armed researchers with new powerful tools to unveil the
Ferreira, B I +2 more
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The CRISPR-Cas system in Enterobacteriaceae [PDF]
Pathogens and Disease, 2018 In nature, microorganisms are constantly exposed to multiple viral infections and thus have developed many strategies to survive phage attack and invasion by foreign DNA. One of such strategies is the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated proteins (Cas) bacterial immunological system.
Liliana, Medina-Aparicio +4 more
openaire +2 more sources