Results 81 to 90 of about 2,009 (183)
Table_1_GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility.xlsx
, 2021 The trafficking of T-cells through peripheral tissues and into afferent lymphatic vessels is essential for immune surveillance and an adaptive immune response.
Brandon Han Siang Wong (11848970) +6 more
core +1 more source
Molecular Brain, 2020 Calcium dysregulation is a key pathological event in Alzheimer’s disease (AD). In studying approaches to mitigate this calcium overload, we identified the collapsin response mediator protein 2 (CRMP2), an axonal guidance protein that participates in ...
Baochang Qi +6 more
doaj +1 more source
Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity
The Journal of Physiology, Volume 603, Issue 15, Page 4237-4253, 1 August 2025.Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez +3 more
wiley +1 more source
, 2009 Collapsin response mediator protein-2 (CRMP2) was recently identified as a physiological substrate for GSK3 and Cdk5, two protein kinases suggested to exhibit greater activity in Alzheimer's disease (AD). Indeed, phosphorylation of CRMP2, at the residues
Thornhill, P. +3 more
core +1 more source
Human Brain Mapping, Volume 46, Issue 10, July 2025.This study highlights the strong correlation between functional language lateralization and gray matter structure, revealing how hemispheric asymmetries in language influence memory organization. Targeted language laterality indices (LIs) provide effective discrimination between temporal lobe epilepsy patients and matched healthy participants, with the
Ankeeta Ankeeta +5 more
wiley +1 more source
, 2022 Chronic neuropathic pain results from a malfunction of the sensory nervous system initially wired to perceive pain as a protective mechanism against tissue injury and damage.
Boinon, Lisa
core
Toxicological Sciences, 2019 Abstract Dexmedetomidine has been reported to ameliorate propofol-induced neurotoxicity in neonatal animals. However, the underlying mechanism is still undetermined. Glycogen synthase kinase-3β (GSK-3β), cycline-dependent kinase-5 (CDK5), and Rho-kinase (RhoA) pathways play critical roles in neuronal development.
Junhua Li +7 more
openaire +2 more sources
Acta Neuropathologica Communications, 2020 The accumulation of phosphorylated tau protein (pTau) in the entorhinal cortex (EC) is the earliest tau pathology in Alzheimer’s disease (AD). Tau tubulin kinase-1 (TTBK1) is a neuron-specific tau kinase and expressed in the EC and hippocampal regions in
Seiko Ikezu +5 more
doaj +1 more source
Video_2_GSK3β Interacts With CRMP2 and Notch1 and Controls T-Cell Motility.mp4
, 2021 The trafficking of T-cells through peripheral tissues and into afferent lymphatic vessels is essential for immune surveillance and an adaptive immune response.
Brandon Han Siang Wong (11848970) +6 more
core +1 more source
Epilepsia, Volume 66, Issue 5, Page 1599-1612, May 2025.Abstract Objective Subjects with left temporal lobe epilepsy may either show altered hemispheric language lateralization or retain typical, left lateralization. Examining the integrity of white matter pathways involved in the adaptation or maintenance of language lateralization in these patients could have important clinical implications for preserving
Salvatore Citro +7 more
wiley +1 more source