Results 71 to 80 of about 494,021 (266)
Demand and Supply of Crop Infraspecific Diversity on Farms: Towards a Policy Framework for On-Farm Conservation [PDF]
Interest is increasing worldwide in on-farm conservation as a component of a strategy to conserve crop genetic resources. On-farm conservation may require outside support to small-scale farmers in areas of crop domestication and diversity.
Bellon, Mauricio R.
core +1 more source
A participatory modeling method for multi-points of view description of a system from scientist's perceptions : application in seed systems modeling in Mali and Chile [PDF]
, 2011 This paper presents a participatory modeling for multi-points of view description of a system from scientists' knowledge. The method is applied in the development of a generic model for agro-biodiversity dynamics in developing countries with a focus on ...
Bazile, Didier +4 more
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Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
THE DETERMINANTS OF CEREAL CROP DIVERSITY ON FARMS IN THE ETHIOPIAN HIGHLANDS [PDF]
On farm conservation of crop diversity entails policy challenges, especially when the diversity of crops maintained on farms has both inter-specific (among crops) and infra-specific (within a crop) components.
Benin, Samuel +4 more
core +1 more source
ARCAD- Agropolis Resource Center for Crop Conservation, Adaptation and Diversity : a new open multi-function platform devoted to agrobiodiversity. Objectives and challenges [PDF]
, 2009 ARCAD, short for Agropolis Resource Center for Crop Conservation, Adaptation and Diversity, is an initiative supported by Agropolis Fondation, the Region Languedoc Roussillon (France) and several French research institutions.
Labouisse, Jean-Pierre, Pham, Jean Louis
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
BMC Research NotesObjective Plants control the direction of root growth toward moisture due to their sessile nature, a phenomenon known as hydrotropism. In Arabidopsis thaliana, the MIZU-KUSSEI1 (MIZ1) protein is essential for the hydrotropic response.
Su-Hwan Kwak, Wonkeun John Park
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso +4 more
wiley +1 more source